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BIOMD0000000392 - Arnold2011_Laisk2006_CalvinCycle_Starch_Sucrose

 

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Reference Publication
Publication ID: 22001849
Arnold A, Nikoloski Z.
A quantitative comparison of Calvin-Benson cycle models.
Trends Plant Sci. 2011 Dec; 16(12): 676-683
Institute of Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany.  [more]
Model
Original Model: BIOMD0000000392.origin
Submitter: Anne Arnold
Submission ID: MODEL1109270008
Submission Date: 27 Sep 2011 11:20:21 UTC
Last Modification Date: 08 Apr 2016 17:13:16 UTC
Creation Date: 19 Oct 2011 14:54:38 UTC
Encoders:  Vijayalakshmi Chelliah
   Anne Arnold
   Zoran Nikoloski
set #1
bqbiol:hasTaxon Taxonomy Viridiplantae
set #2
bqbiol:hasTaxon Taxonomy Mammalia
set #3
bqbiol:encodes Gene Ontology reductive pentose-phosphate cycle
Notes

This model is from the article:
A quantitative comparison of Calvin–Benson cycle models
Anne Arnold, Zoran Nikoloski Trends in Plant Science2011 Oct 14. 22001849,
Abstract:
The Calvin-Benson cycle (CBC) provides the precursors for biomass synthesis necessary for plant growth. The dynamic behavior and yield of the CBC depend on the environmental conditions and regulation of the cellular state. Accurate quantitative models hold the promise of identifying the key determinants of the tightly regulated CBC function and their effects on the responses in future climates. We provide an integrative analysis of the largest compendium of existing models for photosynthetic processes. Based on the proposed ranking, our framework facilitates the discovery of best-performing models with regard to metabolomics data and of candidates for metabolic engineering.

Note: Model of the Calvin cycle and the related end-product pathways to starch and sucrose synthesis by Laisk et al. (2006, DOI:10.1007/s11120-006-9109-1) and the personally provided implementation to Laisk et al. (2009, DOI:10.1007/978-1-4020-9237-4_13).

A reduced version of the published model is implemented (light-dependent reactions are taken out). The parameter values are widely taken from Laisk et al. (1989, [click here for PDF]). The initial metabolite values are chosen from the data set of Zhu et al. (2007, DOI:10.1104/pp.107.103713). A detailed description of all modifications is given in the model described by Arnold and Nikoloski (2011, PMID:22001849.
Model
Publication ID: 22001849 Submission Date: 27 Sep 2011 11:20:21 UTC Last Modification Date: 08 Apr 2016 17:13:16 UTC Creation Date: 19 Oct 2011 14:54:38 UTC
Mathematical expressions
Reactions
RuBisCO (1) RuBisCO (2) - V(CO2) RuBisCO (4) RuBisCO (5) - EP
RuBisCO (5) - EOP RuBisCO (6) - V(O2) RuBisCO (7) PGA kinase
Aldolase (FBP) FBPase Transketolase (F6P) Aldolase (SBP)
SBPase Transketolase (S7P) Ru5P kinase ATP synthase
AGPase Starch synthase TPT (TP) TPT (PGA)
cyt. Aldolase (FBP) cyt. FBPase UGPase Sucrose synthase
Sucrose phosphatase F6Pc kinase F26BPc phosphatase  
Rules
Assignment Rule (variable: ADPc) Assignment Rule (variable: GAP) Assignment Rule (variable: Ru5P) Assignment Rule (variable: F6P)
Assignment Rule (variable: Pic) Assignment Rule (variable: X5P) Assignment Rule (variable: G6P) Assignment Rule (variable: G1P)
Assignment Rule (variable: G1Pc) Assignment Rule (variable: DHAP) Assignment Rule (variable: G6Pc) Assignment Rule (variable: F6Pc)
Assignment Rule (variable: R5P) Assignment Rule (variable: ADP) Assignment Rule (variable: Pi) Assignment Rule (variable: GAPc)
Assignment Rule (variable: DHAPc) Assignment Rule (variable: CO2) Assignment Rule (variable: E) Assignment Rule (variable: W4)
Physical entities
Compartments Species
chloroplast RuBP E ER
EPP EPG EP
EOP PGA TP
GAP DHAP FBP
HeP F6P G6P
G1P E4P SBP
S7P PeP X5P
R5P Ru5P ADPG
ATP ADP Pi
PiPi H CO2
O2 NADPH NADP
     
cytosol PGAc TPc GAPc
DHAPc FBPc F26BPc
HePc F6Pc G6Pc
G1Pc UDPGc UTPc
UDPc ATPc ADPc
SucPc Succ Pic
PiPic Hc  
Global parameters
Et ADT ADTc UDTc
NADPT PiT PiTc q12
Kp12 q1 W4 V28
Reactions (27)
 
 RuBisCO (1) [RuBP] + [E] ↔ [ER];  
 
 RuBisCO (2) - V(CO2) [ER] + [CO2] → [EPP];  
 
 RuBisCO (4) [EPP] ↔ [PGA] + [EP];  
 
 RuBisCO (5) - EP [EP] ↔ [PGA] + [E];  
 
 RuBisCO (5) - EOP [EOP] ↔ ;  
 
 RuBisCO (6) - V(O2) [ER] + [O2] + 0.5 × [ATP] → [EPG] + 0.5 × [PGA] + 0.5 × [ADP];  
 
 RuBisCO (7) [EPG] → [EP];  
 
 PGA kinase [PGA] + [ATP] ↔ [TP] + [ADP] + [Pi];   {GAP}
 
 Aldolase (FBP) 2.0 × [TP] ↔ [FBP];   {GAP} , {DHAP}
 
 FBPase [FBP] ↔ [HeP] + [Pi];   {F6P}
 
 Transketolase (F6P) [HeP] + [TP] ↔ [E4P] + [PeP];   {F6P} , {GAP} , {X5P} , {S7P} , {R5P}
 
 Aldolase (SBP) [E4P] + [TP] ↔ [SBP];   {DHAP}
 
 SBPase [SBP] ↔ [S7P] + [Pi];  
 
 Transketolase (S7P) [S7P] + [TP] ↔ 2.0 × [PeP];   {GAP} , {R5P} , {X5P} , {F6P} , {E4P}
 
 Ru5P kinase [PeP] + [ATP] ↔ [RuBP] + [ADP];   {Ru5P}
 
 ATP synthase [ADP] + [Pi] ↔ [ATP];  
 
 AGPase [HeP] + [ATP] ↔ [ADPG] + [PiPi];   {G1P} , {PGA} , {Pi}
 
 Starch synthase [ADPG] ↔ [ADP];  
 
 TPT (TP) [TP] ↔ [TPc];   {PGA} , {Pi} , {PGAc} , {Pic}
 
 TPT (PGA) [PGA] ↔ [PGAc];   {TP} , {Pi} , {TPc} , {Pic}
 
 cyt. Aldolase (FBP) 2.0 × [TPc] ↔ [FBPc];   {GAPc} , {DHAPc}
 
 cyt. FBPase [FBPc] ↔ [HePc] + [Pic];   {F6Pc} , {F26BPc}
 
 UGPase [HePc] + [UTPc] ↔ [UDPGc] + [PiPic];   {G1Pc}
 
 Sucrose synthase [HePc] + [UDPGc] ↔ [UDPc] + [SucPc] + [Hc];   {F6Pc} , {Pic}
 
 Sucrose phosphatase [SucPc] ↔ [Succ] + [Pic];  
 
 F6Pc kinase [HePc] → [F26BPc] + [ADPc];   {F6Pc} , {Pic} , {TPc} , {PGAc}
 
 F26BPc phosphatase [F26BPc] → [HePc] + [Pic];   {F6Pc} , {TPc} , {PGAc} , {Pic} , {HePc}
 
Rules (20)
 
 Assignment Rule (name: ADPc) ADPc = ADTc-ATPc
 
 Assignment Rule (name: GAP) GAP = TP/(1+1.0007329)
 
 Assignment Rule (name: Ru5P) Ru5P = PeP*0.99974/(1+0.99974+0.99974/1.000053)
 
 Assignment Rule (name: F6P) F6P = HeP*0.999837/(1+0.999837+0.999308)
 
 Assignment Rule (name: Pic) Pic = (PiTc-2*(FBPc+UTPc+ATPc+PiPic))-(PGAc+TPc+HePc+SucPc+UDPGc+UDPc+ADPc)
 
 Assignment Rule (name: X5P) X5P = PeP*0.99974/1.000053/(1+0.99974+0.99974/1.000053)
 
 Assignment Rule (name: G6P) G6P = HeP/(1+0.999837+0.999308)
 
 Assignment Rule (name: G1P) G1P = HeP*0.999308/(1+0.999837+0.999308)
 
 Assignment Rule (name: G1Pc) G1Pc = HePc*0.999308/(1+0.999837+0.999308)
 
 Assignment Rule (name: DHAP) DHAP = 1.0007329*TP/(1+1.0007329)
 
 Assignment Rule (name: G6Pc) G6Pc = HePc/(1+0.999837+0.999308)
 
 Assignment Rule (name: F6Pc) F6Pc = HePc*0.999837/(1+0.999837+0.999308)
 
 Assignment Rule (name: R5P) R5P = PeP/(1+0.99974+0.99974/1.000053)
 
 Assignment Rule (name: ADP) ADP = ADT-ATP
 
 Assignment Rule (name: Pi) Pi = (PiT-2*(EPP+EPG+RuBP+FBP+SBP+ATP+PiPi))-(EP+PGA+TP+HeP+E4P+S7P+PeP+ADP+ADPG)
 
 Assignment Rule (name: GAPc) GAPc = TPc/(1+1.0007329)
 
 Assignment Rule (name: DHAPc) DHAPc = 1.0007329*TPc/(1+1.0007329)
 
 Assignment Rule (name: CO2) CO2 = (1.2E-5/(0.38+0.015)+8*4*0.00055*3030.3*ER*O2/2)/(1/(0.38+0.015)+8*4*0.00055*300000*ER)
 
 Assignment Rule (name: E) E = Et-(ER+EPP+EPG+EP+EOP)
 
 Assignment Rule (name: W4) W4 = 6*EOP-70000*Pi*E
 
Functions (14)
 
 Constant flux (reversible) lambda(v, v)
 
 cyt. FBPase lambda(Vm, s1, p1, p2, q, Ks1, r1, Kr1, Kp1, Kp2, Vm*s1*(s1-p1*p2/q)/((Ks1*(1+r1/Kr1))^2*((s1/(Ks1*(1+r1/Kr1)))^2+(1+p1/Kp1)*(1+p2/Kp2))))
 
 TPTout lambda(Vm, s, Ks, r1, Kr1, r2, Kr2, p, Kp, r3, Kr3, r4, Kr4, Vm/(s/Ks+r1/Kr1+r2/Kr2+p/Kp+r3/Kr3+r4/Kr4+(s/Ks+r1/Kr1+r2/Kr2)*(p/Kp+r3/Kr3+r4/Kr4))*(s*(p/Kp+r3/Kr3+r4/Kr4)/Ks-p*(s/Ks+r1/Kr1+r2/Kr2)/Kp))
 
 MM s1p1 - reg lambda(Vm, s1, p1, q, Ks1, Kp1, Vm*(s1-p1/q)/(Ks1*(1+s1/Ks1+p1/Kp1)))
 
 F6Pc kinase lambda(Vm, s1, Ks1, r1, Kr1, r2, r3, Kr2, Vm*s1/Ks1*(1+r1/Kr1)/(1+(r2+r3)/Kr2))
 
 MM s2p2 - reg lambda(s1, s2, p1, p2, q, Ks1, Ks2, Kp1, Kp2, Vm, Vm*(s1*s2-p1*p2/q)/(Ks1*Ks2*(((1+s1/Ks1)*(1+s2/Ks2)+(1+p1/Kp1)*(1+p2/Kp2))-1)))
 
 MM s2p2 + reg 1*x,1*a lambda(Vm, r1, r2, s1, s2, p1, p2, q, Ks1, Ks2, Kp1, Kp2, Vm*(r1/r2)^2*(s1*s2-p1*p2/q)/(Ks1*Ks2*(((1+s1/Ks1)*(1+s2/Ks2)+(1+p1/Kp1)*(1+p2/Kp2))-1)))
 
 MMlike s2p3 - reg lambda(Vm, s1, s2, p1, p2, p3, q, Ks1, Ks2, Kp1, Kp2, Kp3, Vm*(s1*s2-p1*p2*p3/q)/(Ks1*Ks2*((1+s1/Ks1)*(1+s2/Ks2)+p1/Kp1+p2/Kp2+p3/Kp3+p1*p2*p3/(Kp1*Kp2*Kp3))))
 
 F26BPc phosphatase lambda(Vm, s1, Ks1, r1, r2, Kr1, r3, Kr3, r4, Kr4, Vm*s1/Ks1*(1+(r1+r2)/Kr1)/(1+r3/Kr3+r4/Kr4))
 
 Sucrose synthase lambda(Vm, s1, s2, p1, p2, p3, q, Ks1, r1, Kr11, Ks2, Kp1, Kp2, Kr12, Vm*s1*(s1*s2-p1*p2*p3/q)/((Ks1*(1+r1/Kr11))^2*Ks2*((((1+(s1/(Ks1*(1+r1/Kr11)))^2)*(1+s2/Ks2)+(1+p1/Kp1)*(1+p2/Kp2))-1)+r1/Kr12)))
 
 MMlike s1p2 - reg + no p2 alone lambda(Vm, s1, p1, p2, q, Ks1, Kp1, Kp2, Vm*(s1-p1*p2/q)/(Ks1*(1+s1/Ks1+p1/Kp1+p1*p2/(Kp1*Kp2))))
 
 Transketolase lambda(Vm, q, s1, s2, p1, p2, K1, K2, K1s2, K2s1, r1, K2r1, K2s2, r2, Vm*(q*s1*s2-p1*p2)/(K1*K2*(1+(1+s2/K1s2)*(s1/K2s1+r1/K2r1)+s2/K2s2+1/K2*(p2*(1+p1*r2/K1)+p1+r2))))
 
 MM s2p1 - reg lambda(s1, s2, p1, q, Ks1, Ks2, Kp1, Vm, Vm*(s1*s2-p1/q)/(Ks1*Ks2*((1+s1/Ks1)*(1+s2/Ks2)+p1/Kp1)))
 
 MM s1p2 - reg lambda(Vm, s1, p1, p2, q, Ks1, Kp1, Kp2, Vm*(s1-p1*p2/q)/(Ks1*(s1/Ks1+(1+p1/Kp1)*(1+p2/Kp2))))
 
   chloroplast Spatial dimensions: 3.0  Compartment size: 1.0
 
 RuBP
Compartment: chloroplast
Initial concentration: 0.002
 
  E
Compartment: chloroplast
Initial concentration: 9.2303030303025E-6
 
   ER
Compartment: chloroplast
Initial concentration: 0.001201
 
   EPP
Compartment: chloroplast
Initial concentration: 2.711E-4
 
   EPG
Compartment: chloroplast
Initial concentration: 3.206E-4
 
   EP
Compartment: chloroplast
Initial concentration: 7.045E-4
 
   EOP
Compartment: chloroplast
Initial concentration: 2.966E-4
 
 PGA
Compartment: chloroplast
Initial concentration: 0.0024
 
 TP
Compartment: chloroplast
Initial concentration: 5.0E-4
 
  GAP
Compartment: chloroplast
Initial concentration: 2.49908421059103E-4
 
  DHAP
Compartment: chloroplast
Initial concentration: 2.50091578940897E-4
 
 FBP
Compartment: chloroplast
Initial concentration: 6.7E-4
 
 HeP
Compartment: chloroplast
Initial concentration: 0.0022
 
  F6P
Compartment: chloroplast
Initial concentration: 7.33422825505269E-4
 
  G6P
Compartment: chloroplast
Initial concentration: 7.33542392915314E-4
 
  G1P
Compartment: chloroplast
Initial concentration: 7.33034781579417E-4
 
 E4P
Compartment: chloroplast
Initial concentration: 5.0E-5
 
 SBP
Compartment: chloroplast
Initial concentration: 3.0E-4
 
 S7P
Compartment: chloroplast
Initial concentration: 0.002
 
 PeP
Compartment: chloroplast
Initial concentration: 2.5E-4
 
  X5P
Compartment: chloroplast
Initial concentration: 8.33231656462569E-5
 
  R5P
Compartment: chloroplast
Initial concentration: 8.33492525797069E-5
 
  Ru5P
Compartment: chloroplast
Initial concentration: 8.33275817740362E-5
 
 ADPG
Compartment: chloroplast
Initial concentration: 6.295E-6
 
 ATP
Compartment: chloroplast
Initial concentration: 6.8E-4
 
  ADP
Compartment: chloroplast
Initial concentration: 8.2E-4
 
  Pi
Compartment: chloroplast
Initial concentration: 0.0109928959090909
 
   PiPi
Compartment: chloroplast
Initial concentration: 1.0E-6
Constant
 
   H
Compartment: chloroplast
Initial concentration: 0.0891250931577478
Constant
 
  CO2
Compartment: chloroplast
Initial concentration: 4.36233478328384E-6
 
 O2
Compartment: chloroplast
Initial concentration: 2.6E-4
Constant
 
 NADPH
Compartment: chloroplast
Initial concentration: 2.1E-4
Constant
 
 NADP
Compartment: chloroplast
Initial concentration: 2.9E-4
Constant
 
   cytosol Spatial dimensions: 3.0  Compartment size: 1.0
 
 PGAc
Compartment: cytosol
Initial concentration: 0.0
 
 TPc
Compartment: cytosol
Initial concentration: 0.0023
 
  GAPc
Compartment: cytosol
Initial concentration: 0.00114957873687187
 
  DHAPc
Compartment: cytosol
Initial concentration: 0.00115042126312813
 
 FBPc
Compartment: cytosol
Initial concentration: 0.002
 
 F26BPc
Compartment: cytosol
Initial concentration: 7.8E-9
 
 HePc
Compartment: cytosol
Initial concentration: 0.0058
 
  F6Pc
Compartment: cytosol
Initial concentration: 0.00193356926724116
 
  G6Pc
Compartment: cytosol
Initial concentration: 0.0019338844904131
 
  G1Pc
Compartment: cytosol
Initial concentration: 0.00193254624234574
 
 UDPGc
Compartment: cytosol
Initial concentration: 5.7E-4
 
 UTPc
Compartment: cytosol
Initial concentration: 3.6E-4
Constant
 
 UDPc
Compartment: cytosol
Initial concentration: 6.4E-4
Constant
 
 ATPc
Compartment: cytosol
Initial concentration: 3.6E-4
Constant
 
  ADPc
Compartment: cytosol
Initial concentration: 6.4E-4
 
 SucPc
Compartment: cytosol
Initial concentration: 0.0
 
 Succ
Compartment: cytosol
Initial concentration: 0.0
Constant
 
  Pic
Compartment: cytosol
Initial concentration: 0.00157545454545454
 
   PiPic
Compartment: cytosol
Initial concentration: 4.0E-5
Constant
 
 Hc
Compartment: cytosol
Initial concentration: 0.158489318357816
Constant
 
Global Parameters (12)
 
 Et
Value: 0.0028030303030303
Constant
 
 ADT
Value: 0.0015
Constant
 
 ADTc
Value: 0.001
Constant
 
 UDTc
Value: 0.001
Constant
 
 NADPT
Value: 5.0E-4
Constant
 
 PiT
Value: 0.0284090909090909
Constant
 
 PiTc
Value: 0.0170454545454545
Constant
 
 q12
Value: 2.22786254125735E12
Constant
 
 Kp12
Value: 224014.808032967
Constant
 
 q1
Value: 0.129053067280279
Constant
 
  W4
Value: -0.00532314322950372
 
 V28
Value: 7.386364E-5
Constant
 
RuBisCO (1) (2)
 
 k1
Value: 50000.0
Constant
 
 k2
Value: 0.9
Constant
 
RuBisCO (2) - V(CO2) (1)
 
 k1
Value: 300000.0
Constant
 
RuBisCO (4) (2)
 
 k1
Value: 6.0
Constant
 
 k2
Constant
 
RuBisCO (5) - EP (2)
 
 k1
Value: 6.0
Constant
 
 k2
Value: 70000.0
Constant
 
RuBisCO (6) - V(O2) (1)
 
 k1
Value: 3030.3
Constant
 
RuBisCO (7) (1)
 
 k1
Value: 3.0
Constant
 
PGA kinase (6)
 
 Vm
Value: 0.0170455
Constant
 
 Ks1
Value: 0.0011122
Constant
 
 Ks2
Value: 3.307E-4
Constant
 
 Kp1
Value: 2.7035E-4
Constant
 
 Kp2
Value: 5.3013E-4
Constant
 
 Kp3
Value: 0.0027397
Constant
 
Aldolase (FBP) (5)
 
 q
Value: 1.18815
Constant
 
 Ks1
Value: 2.7035E-4
Constant
 
 Ks2
Value: 3.6393E-4
Constant
 
 Kp1
Value: 2.0129E-5
Constant
 
 Vm
Value: 0.022727
Constant
 
FBPase (5)
 
 Vm
Value: 0.011364
Constant
 
 q
Value: 0.77294
Constant
 
 Ks1
Value: 3.2842E-5
Constant
 
 Kp1
Value: 6.3429E-5
Constant
 
 Kp2
Value: 0.0017914
Constant
 
Transketolase (F6P) (8)
 
 Vm
Value: 0.170455
Constant
 
 q
Value: 0.99943
Constant
 
 K1
Value: 6.1349E-4
Constant
 
 K2
Value: 1.1438E-4
Constant
 
 K1s2
Value: 2.7035E-4
Constant
 
 K2s1
Value: 5.407E-4
Constant
 
 K2r1
Value: 1.7677E-4
Constant
 
 K2s2
Value: 9.0464E-5
Constant
 
Aldolase (SBP) (5)
 
 q
Value: 1.18815
Constant
 
 Ks1
Value: 1.7677E-4
Constant
 
 Ks2
Value: 3.6393E-4
Constant
 
 Kp1
Value: 2.0129E-5
Constant
 
 Vm
Value: 0.011364
Constant
 
SBPase (5)
 
   Vm
Value: 0.00568182
Constant
 
   q
Value: 0.77294
Constant
 
   Ks1
Value: 1.2713E-5
Constant
 
   Kp1
Value: 1.5597E-5
Constant
 
   Kp2
Value: 0.006744
Constant
 
Transketolase (S7P) (8)
 
   Vm
Value: 0.0821023
Constant
 
   q
Value: 0.99996
Constant
 
   K1
Value: 6.1349E-4
Constant
 
   K2
Value: 1.1438E-4
Constant
 
   K1s2
Value: 2.7035E-4
Constant
 
   K2s1
Value: 1.7677E-4
Constant
 
   K2r1
Value: 5.407E-4
Constant
 
   K2s2
Value: 9.0464E-5
Constant
 
Ru5P kinase (6)
 
   q
Value: 1.05289
Constant
 
   Ks1
Value: 3.63934E-5
Constant
 
   Ks2
Value: 5.5117E-4
Constant
 
   Kp1
Value: 9.95868E-5
Constant
 
   Kp2
Value: 9.11825E-5
Constant
 
   Vm
Value: 0.568182
Constant
 
ATP synthase (3)
 
   Ks1
Value: 3.1808E-4
Constant
 
   Ks2
Value: 3.1612E-4
Constant
 
   Vm
Value: 0.0284091
Constant
 
AGPase (6)
 
   Vm
Value: 0.00113636
Constant
 
   q
Value: 0.11059
Constant
 
   Ks1
Value: 0.0010398
Constant
 
   Ks2
Value: 1.1023E-4
Constant
 
   Kp1
Value: 5.3013E-4
Constant
 
   Kp2
Value: 0.01951
Constant
 
Starch synthase (4)
 
   Vm
Value: 0.00284091
Constant
 
   q
Value: 1.00326
Constant
 
   Ks1
Value: 2.12052E-4
Constant
 
   Kp1
Value: 6.36157E-4
Constant
 
TPT (TP) (7)
 
   Vm
Value: 0.0568182
Constant
 
   Ks
Value: 9.3583E-5
Constant
 
   Kr1
Value: 8.9213E-4
Constant
 
   Kr2
Value: 9.8597E-5
Constant
 
   Kp
Value: 9.6372E-5
Constant
 
   Kr3
Value: 5.4107E-4
Constant
 
   Kr4
Value: 9.4837E-5
Constant
 
TPT (PGA) (7)
 
   Vm
Value: 0.0568182
Constant
 
   Ks
Value: 8.9213E-4
Constant
 
   Kr1
Value: 9.3583E-5
Constant
 
   Kr2
Value: 9.8597E-5
Constant
 
   Kp
Value: 5.4107E-4
Constant
 
   Kr3
Value: 9.6372E-5
Constant
 
   Kr4
Value: 9.4837E-5
Constant
 
cyt. Aldolase (FBP) (5)
 
   q
Value: 1.00224
Constant
 
   Ks1
Value: 2.78407E-4
Constant
 
   Ks2
Value: 3.74778E-4
Constant
 
   Kp1
Value: 2.10226E-5
Constant
 
   Vm
Value: 0.00568182
Constant
 
cyt. FBPase (6)
 
   Vm
Value: 0.00113636
Constant
 
   q
Value: 0.792367
Constant
 
   Ks1
Value: 2.2129E-5
Constant
 
   Kr1
Value: 1.1065E-6
Constant
 
   Kp1
Value: 6.5319E-5
Constant
 
   Kp2
Value: 0.0018624
Constant
 
UGPase (6)
 
   q
Value: 1.6219
Constant
 
   Ks1
Value: 3.2124E-5
Constant
 
   Ks2
Value: 2.364E-4
Constant
 
   Kp1
Value: 1.4393E-4
Constant
 
   Kp2
Value: 0.0013192
Constant
 
   Vm
Value: 0.00410568
Constant
 
Sucrose synthase (8)
 
   Vm
Value: 7.38636E-5
Constant
 
   q
Value: 1.00012
Constant
 
   Ks1
Value: 2.78407E-4
Constant
 
   Kr11
Value: 0.00920241
Constant
 
   Ks2
Value: 1.10717E-4
Constant
 
   Kp1
Value: 6.42157E-4
Constant
 
   Kp2
Value: 3.74778E-4
Constant
 
   Kr12
Value: 0.00164329
Constant
 
Sucrose phosphatase (5)
 
   Vm
Value: 0.0010267
Constant
 
   q
Value: 1.35286
Constant
 
   Ks1
Value: 5.354E-5
Constant
 
   Kp1
Value: 0.01
Constant
 
   Kp2
Value: 0.002191
Constant
 
F6Pc kinase (4)
 
   Vm
Value: 1.02614E-7
Constant
 
   Ks1
Value: 0.001
Constant
 
   Kr1
Value: 0.001
Constant
 
   Kr2
Value: 0.0015
Constant
 
F26BPc phosphatase (5)
 
   Vm
Value: 2.05284E-10
Constant
 
   Ks1
Value: 1.0E-9
Constant
 
   Kr1
Value: 0.002
Constant
 
   Kr3
Value: 0.001
Constant
 
   Kr4
Value: 1.0E-4
Constant
 
Representative curation result(s)
Representative curation result(s) of BIOMD0000000392

Curator's comment: (updated: 19 Oct 2011 15:47:37 BST)

The steady state concentration of the metabolites involved are reproduced here. This is the reproduction of the Table S7 (referring Laisk 2006) of the reference (supp. material) publication. The simulation was done using Copasi v4.7 (Build 34).

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