BioModels Database

Reactions (28)

Caspase 9 / Apaf-1 binding

[APAF-1] + [Caspase 9] ↔ [APAF-1-Caspase 9 complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology protein binding

Caspase 3 cleavage by Caspase 9

[Caspase 3] + [Caspase 9] → [Caspase 3 cleaved] + [Caspase 9];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:is

Enzyme Nomenclature 3.4.22.62

set #2

bqbiol:isVersionOf

Gene Ontology caspase activity

set #3

bqbiol:isVersionOf

Gene Ontology activation of cysteine-type endopeptidase activity involved in apoptotic process

Caspase 3 cleavage by Caspase 9-Apaf-1

[Caspase 3] + [APAF-1-Caspase 9 complex] → [Caspase 3 cleaved] + [APAF-1-Caspase 9 complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology activation of cysteine-type endopeptidase activity involved in apoptotic process

Caspase 9 Xiap binding

[Caspase 9] + [XIAP] ↔ [Caspase 9-XIAP complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology protein binding

set #2

bqbiol:isVersionOf

Gene Ontology cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Caspase 9-Apaf-1 Xiap binding

[APAF-1-Caspase 9 complex] + [XIAP] ↔ [APAF-1-Caspase 9-XIAP complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology protein binding

set #2

bqbiol:isVersionOf

Gene Ontology cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Caspase 9-Xiap Apaf-1 binding

[Caspase 9-XIAP complex] + [APAF-1] ↔ [APAF-1-Caspase 9-XIAP complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology protein binding

cleaved Caspase 3-Xiap binding

[Caspase 3 cleaved] + [XIAP] ↔ [Caspase 3 cleaved - XIAP complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology protein binding

set #2

bqbiol:isVersionOf

Gene Ontology cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Caspase 9 cleavage by cleaved caspase 3

[Caspase 9] + [Caspase 3 cleaved] → [Caspase 9 cleaved] + [Caspase 3 cleaved];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:is

Enzyme Nomenclature 3.4.22.56
Gene Ontology caspase activity

Caspase 9 cleavage by cleaved caspase 3 when Apaf-1 is bound

[APAF-1-Caspase 9 complex] + [Caspase 3 cleaved] → [APAF-1-Caspase 9 cleaved complex] + [Caspase 3 cleaved];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:is

Enzyme Nomenclature 3.4.22.56
Gene Ontology caspase activity

cleaved Caspase 9 Apaf-1 binding

[Caspase 9 cleaved] + [APAF-1] ↔ [APAF-1-Caspase 9 cleaved complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology protein binding

cleaved Caspase 9 XIAP binding

[Caspase 9 cleaved] + [XIAP] ↔ [Caspase 9 cleaved-XIAP complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cysteine-type endopeptidase inhibitor activity involved in apoptotic process

set #2

bqbiol:isVersionOf

Gene Ontology protein binding

cleaved Caspase 9-Apaf-1 XIAP binding

[APAF-1-Caspase 9 cleaved complex] + [XIAP] ↔ [Apaf-1-Caspase 9 cleaved -XIAP complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cysteine-type endopeptidase inhibitor activity involved in apoptotic process

set #2

bqbiol:isVersionOf

Gene Ontology protein binding

cleaved Caspase 9-Xiap Apaf-1 binding

[Caspase 9 cleaved-XIAP complex] + [APAF-1] ↔ [Apaf-1-Caspase 9 cleaved -XIAP complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology protein binding

Caspase 3 cleavage by cleaved Caspase 9

[Caspase 3] + [Caspase 9 cleaved] → [Caspase 3 cleaved] + [Caspase 9 cleaved];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology caspase activity

set #2

bqbiol:is

Enzyme Nomenclature 3.4.22.62

Caspase 3 cleavage by cleaved Caspase 9 - Apaf-1

[Caspase 3] + [APAF-1-Caspase 9 cleaved complex] → [Caspase 3 cleaved] + [APAF-1-Caspase 9 cleaved complex];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology caspase activity

set #2

bqbiol:is

Enzyme Nomenclature 3.4.22.62

Apaf-1 turnover

→ [APAF-1];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Caspase 9 turnover

→ [Caspase 9];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Xiap turnover

→ [XIAP];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Caspase 9-Xiap degradation

[Caspase 9-XIAP complex] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Apaf-1-Caspase 9-Xiap degradation

[APAF-1-Caspase 9-XIAP complex] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Apaf-1-Caspase 9 degradation

[APAF-1-Caspase 9 complex] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Caspase 3 turnover

→ [Caspase 3];

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Caspase 3 cleaved degradation

[Caspase 3 cleaved] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Caspase 3 cleaved-Xiap degradation

[Caspase 3 cleaved - XIAP complex] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Caspase 9 cleaved-Xiap degradation

[Caspase 9 cleaved-XIAP complex] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Caspase 9 cleaved degradation

[Caspase 9 cleaved] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Apaf-1 Caspase 9 cleaved degradation

[APAF-1-Caspase 9 cleaved complex] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

Apaf-1 Caspase 9 cleaved-Xiap degradation

[Apaf-1-Caspase 9 cleaved -XIAP complex] → ;

Math:

(Details: $View Math$ )

Annotations:

set #1

bqbiol:isVersionOf

Gene Ontology cellular protein catabolic process

BioModels Database

BIOMD0000000102 - Legewie2006_apoptosis_WT

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