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BIOMD0000000052 - Brands2002 - Monosaccharide-casein systems

 

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Reference Publication
Publication ID: 12405768
Brands CM, van Boekel MA.
Kinetic modeling of reactions in heated monosaccharide-casein systems.
J. Agric. Food Chem. 2002 Nov; 50(23): 6725-6739
Department of Agrotechnology and Food Sciences, Product Design and Quality Management Group, Wageningen University, P.O. Box 8129, 6700 EV Wageningen, The Netherlands.  [more]
Model
Original Model: BIOMD0000000052.origin
Submitter: Harish Dharuri
Submission ID: MODEL8177704759
Submission Date: 25 Jan 2006 22:00:14 UTC
Last Modification Date: 04 Apr 2014 12:30:26 UTC
Creation Date: 25 Jan 2006 22:00:14 UTC
Encoders:  Harish Dharuri
set #1
bqbiol:hasProperty Mathematical Modelling Ontology MAMO_0000046
set #2
bqmodel:isDerivedFrom PubMed 11600005
set #3
bqbiol:isVersionOf Gene Ontology monosaccharide binding
Gene Ontology monosaccharide biosynthetic process
bqbiol:hasTaxon Taxonomy cellular organisms
Notes
Brands2002 - Monosaccharide-casein systems

A kinetic model of the Maillard reaction occurring in heated monosaccharide-casein system.

This model is described in the article:

Brands CM, van Boekel MA
Journal of Agricultural and Food Chemistry. 2002, 50(23):6725-6739

Abstract:

In the present study, a kinetic model of the Maillard reaction occurring in heated monosaccharide-casein systems was proposed. Its parameters, the reaction rate constants, were estimated via multiresponse modeling. The determinant criterion was used as the statistical fit criterion instead of the familiar least squares to avoid statistical problems. The kinetic model was extensively tested by varying the reaction conditions. Different sugars (glucose, fructose, galactose, and tagatose) were studied regarding their effect on the reaction kinetics. This study has shown the power of multiresponse modeling for the unraveling of complicated reaction routes as occur in the Maillard reaction. The iterative process of proposing a model, confronting it with experiments, and criticizing the model was passed through four times to arrive at a model that was largely consistent with all results obtained. A striking difference was found between aldose and ketose sugars as suggested by the modeling results: not the ketoses themselves but only their reaction products were found to be reactive in the Maillard reaction.

To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.

Model
Publication ID: 12405768 Submission Date: 25 Jan 2006 22:00:14 UTC Last Modification Date: 04 Apr 2014 12:30:26 UTC Creation Date: 25 Jan 2006 22:00:14 UTC
Mathematical expressions
Reactions
_J1 _J2 _J3 _J4
_J5 _J6 _J7 _J8
_J9 _J10 _J11  
Physical entities
Compartments Species
compartment Glu Fru Formic_acid
Triose Acetic_acid Cn
Amadori AMP C5
lys_R Melanoidin  
Reactions (11)
 
 _J1 [Glu] → [Fru];  
 
 _J2 [Fru] → [Glu];  
 
 _J3 [Glu] → [C5] + [Formic_acid];  
 
 _J4 [Fru] → [C5] + [Formic_acid];  
 
 _J5 [Fru] → 2.0 × [Triose];  
 
 _J6 [Triose] → [Cn] + [Acetic_acid];  
 
 _J7 [lys_R] + [Glu] → [Amadori];  
 
 _J8 [Amadori] → [Acetic_acid] + [lys_R];  
 
 _J9 [Amadori] → [AMP];  
 
 _J10 [lys_R] + [Fru] → [AMP];  
 
 _J11 [AMP] → [Melanoidin];  
 
   Spatial dimensions: 3.0  Compartment size: 1.0
 
 Glu
Compartment: compartment
Initial concentration: 160.0
 
 Fru
Compartment: compartment
Initial concentration: 0.0
 
 Formic_acid
Compartment: compartment
Initial concentration: 0.0
 
   Triose
Compartment: compartment
Initial concentration: 0.0
 
 Acetic_acid
Compartment: compartment
Initial concentration: 0.0
 
   Cn
Compartment: compartment
Initial concentration: 0.0
 
   Amadori
Compartment: compartment
Initial concentration: 0.0
 
   AMP
Compartment: compartment
Initial concentration: 0.0
 
   C5
Compartment: compartment
Initial concentration: 0.0
 
 lys_R
Compartment: compartment
Initial concentration: 15.0
 
   Melanoidin
Compartment: compartment
Initial concentration: 0.0
 
_J1 (1)
 
   K1
Value: 0.01
Constant
 
_J2 (1)
 
   K2
Value: 0.00509
Constant
 
_J3 (1)
 
   K3
Value: 4.7E-4
Constant
 
_J4 (1)
 
   K4
Value: 0.0011
Constant
 
_J5 (1)
 
   K5
Value: 0.00712
Constant
 
_J6 (1)
 
   K6
Value: 0.00439
Constant
 
_J7 (1)
 
   K7
Value: 1.8E-4
Constant
 
_J8 (1)
 
   K8
Value: 0.11134
Constant
 
_J9 (1)
 
   K9
Value: 0.14359
Constant
 
_J10 (1)
 
   K10
Value: 1.5E-4
Constant
 
_J11 (1)
 
   K11
Value: 0.12514
Constant
 
Representative curation result(s)
Representative curation result(s) of BIOMD0000000052

Curator's comment: (updated: 18 Dec 2006 00:57:07 GMT)

The model reproduces the simulation depicted in Fig 2 for the Glucose-Casein system. The results shown here were obtained from MathSBML.

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