Cell cycle arrest in G2 phase by DNA damage is released before the complete repair of all lesions. Jaiswal et al. (2017) mathematically modelled the ATM,ATR, Wip1 and Plk1 pathways to explore why.
BioModels now hosts 6753 models derived from biological samples collected from patients.
We are extremely happy to announce the 31st release of BioModels. The resource now provides 1640 literature-based models and 143,070 models automatically generated from pathway resources. For more information, please refer to the release notes.
Published in CPT:PSP Mechanistic models on neurodegenerative disease processes