A mathematical model describing the inhibition of IL6 signalling in Crohn's Disease is presented here. Several antibody ligands were simulated with different targets and their varied effects upon IL6 signalling is observed.
The resource now provides a total of 144,282 models and introduces additional features and an easier access to its content thanks to an updated homepage. See the release notes for more details.
BioModels' homepage has been updated to provide a clearer view of the content of the repository. Also, a GO classification is a new browsing tool for models from the literature. Finally, various updates have been implemented for non-curated models.
Our recent review "The impact of mathematical modeling on the understanding of diabetes and related complications" has been the most downloaded this month from the CPT: Pharmacometrics & Systems Pharmacology website!