Alternative Exon Database

PLEASE NOTE

The ASD, ATD, AEdb and ASTD resources will be phased out beginning of 2012.

From now, you can access up-to-date alternative splicing events information through Ensembl

Alternatively, you can retrieve all the archived data from ASD/ATD/ASTD/AEdb projects on the EBI ftp site at ftp.ebi.ac.uk/pub/databases/astd

AEDB is a manual generated database for alternative exons and their properties from numerous species - the data is gathered from literature where these exons have been experimentally verified.

Services

At the moment we have the following AEdb products available:

Sequence	A database of alternative exons.Search via a simple query form. Submission and modification is restricted to consortium members.
Function	A database of functions attributed to constitutive and alternative exon. Search via a simple query form. Submission and modification is restricted to consortium members.
Regulatory sequences	A database of transcript regulatory motifs. Search via a simple query form. Submission and modification is restricted to consortium members.
Minigenes	A table of minigenes and their associations to splicing events.
Diseases	A table of diseases associated with splicing and their associations to AltSplice.

Data files

This ASD database has been generated within a research programme financed by the European Community¹. ExonHit Therapeutics SA has been granted commercial exploitation rights to this database under the EU funded consortium, of which it is a member, and the database is protected by EC Directive ².

ExonHit currently holds an option to an exclusive license to the contents of the Alternative Splicing Database for commercial use including without limitation, providing services, and designing products (Commercial Rights). Consequently, such Commercial Rights are not currently available to anyone else. For up to date contact information for ExonHit Therapeutics SA, please see its website: www.exonhit.com.

The database is covered by paragraphs 2-17 of the EBI's normal terms of use, to be found at www.ebi.ac.uk/Information/termsofuse

By clicking the button below, or hyperlinking to pages beyond this notice, you indicate your agreement with these terms.

¹. DIRECTIVE 96/9/EC OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 11 March 1996 on the legal protection of databases.

². DIRECTIVE 96/9/EC OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 11 March 1996 on the legal protection of databases.

Contact

Scientific contact	Stefam Stamm - Institute of Biochemistry, University Erlangen Nurenberg, 91054 Erlangen, GERMANY Contact: Stefan Stamm
Technical contact	Eleanor Stanley - EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UNITED KINGDOM Contact: Eleanor Stanley

References

An alternative exon database (AEDB) and its statistical analysis.
Stamm, S., J. Zhu, K. Nakai, P. Stoilov, O. Stoss, and M.Q. Zhang.
DNA and Cell Biol., 19: 739-756 (2000).