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ASD - ALTERNATIVE SPLICING


Splice Signal Analysis

Tool

Description

WrapperA wrapper for all the below tools, i.e. Intron Analysis, Regulatory sequences, Exon Finder, Splicing Rainbow, and Blast analysis

Intron AnalysisComputes scores at Donor and Acceptor site; Identifies Branch Point (BP) and Polypyrimidine Tract (PPT) site in an Intronic sequence

Individual analyses of the above Intron Analysis tool:

 Donor score analysisComputes Donor Site Scores
 Acceptor score analysisComputes Acceptor Site Scores
 PPT analysisComputes positions of Polypyrimidine Tract (PPT) in intronic sequence
 BP analysisComputes positions and scores of Branch Point (BP) in intronic sequence

Exon FinderIdentifies potential exons in human genes

ORF and ATG context scoringIdentifies and scores alternative Open Reading Frames (ORF) and translates them into peptides.

Splicing RainbowIdentifies binding sites for splice factors in RNA sequences

Regulatory SequencesAllows to check your sequence against known regulatory sequences, and also allows one to query the regulatory sequence database for specific motifs.

Splice Sequence Search Allows the user to perform Sequence search against AltSplice and AEDB databases (genes, splice patterens, exons, and peptides) via WU-Blast2 or Fasta.

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