Source Name	Comment [Sample_description]	Comment [Sample_source_name]	Comment [Sample_title]	Characteristics [age]	Characteristics [agender]	Term Source REF	Term Accession Number	Characteristics [agenotype]	Characteristics [organism]	Term Source REF	Term Accession Number	Characteristics [strain]	Term Source REF	Term Accession Number	Protocol REF	Term Source REF	Protocol REF	Term Source REF	Protocol REF	Term Source REF	Extract Name	Material Type	Protocol REF	Term Source REF	Labeled Extract Name	Label	Protocol REF	Term Source REF	Assay Name	Array Design REF	Term Source REF	Technology Type	Protocol REF	Term Source REF	Protocol REF	Term Source REF	Normalization Name	Derived Array Data File	Comment [Derived ArrayExpress FTP file]	FactorValue [AGENOTYPE]	FactorValue [TREATMENT]
GSM1139934 1	Liver-Ad Lib- Homozygous knockout	Liver-Ad Lib- Homozygous knockout	Liver-Ad Lib- Homozygous knockout-replicate 4	2-5 months old	male	EFO	EFO_0001266	Homozygous knockout  (SIRT1-/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139934 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139934 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139934	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139934_sample_table.txt norm	GSM1139934_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Homozygous knockout  (SIRT1-/-)	Ad libitum diet
GSM1139933 1	Liver-Ad Lib-Wt	Liver-Ad Lib-Wt	Liver-Ad Lib-Wt-replcate 3	2-5 months old	male	EFO	EFO_0001266	Wild Type  (SIRT1+/+)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139933 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139933 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139933	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139933_sample_table.txt norm	GSM1139933_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Wild Type  (SIRT1+/+)	Ad libitum diet
GSM1139932 1	Liver-Ad Lib-Wt	Liver-Ad Lib-Wt	Liver-Ad Lib-Wt-replcate 2	2-5 months old	male	EFO	EFO_0001266	Wild Type  (SIRT1+/+)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139932 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139932 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139932	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139932_sample_table.txt norm	GSM1139932_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Wild Type  (SIRT1+/+)	Ad libitum diet
GSM1139931 1	Liver-Ad Lib- Heterozygous knockout	Liver-Ad Lib- Heterozygous knockout	Liver-Ad Lib- Heterozygous knockout-replicate 2	2-5 months old	male	EFO	EFO_0001266	Heterozygous knockout  (SIRT1+/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139931 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139931 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139931	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139931_sample_table.txt norm	GSM1139931_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Heterozygous knockout  (SIRT1+/-)	Ad libitum diet
GSM1139930 1	Liver-Ad Lib- Homozygous knockout	Liver-Ad Lib- Homozygous knockout	Liver-Ad Lib- Homozygous knockout-replicate 3	2-5 months old	male	EFO	EFO_0001266	Homozygous knockout  (SIRT1-/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139930 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139930 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139930	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139930_sample_table.txt norm	GSM1139930_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Homozygous knockout  (SIRT1-/-)	Ad libitum diet
GSM1139929 1	Liver-Ad Lib-Wt	Liver-Ad Lib-Wt	Liver-Ad Lib-Wt-replcate 1	2-5 months old	male	EFO	EFO_0001266	Wild Type  (SIRT1+/+)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139929 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139929 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139929	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139929_sample_table.txt norm	GSM1139929_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Wild Type  (SIRT1+/+)	Ad libitum diet
GSM1139928 1	Liver-Ad Lib- Homozygous knockout	Liver-Ad Lib- Homozygous knockout	Liver-Ad Lib- Homozygous knockout-replicate 2	2-5 months old	male	EFO	EFO_0001266	Homozygous knockout  (SIRT1-/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139928 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139928 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139928	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139928_sample_table.txt norm	GSM1139928_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Homozygous knockout  (SIRT1-/-)	Ad libitum diet
GSM1139927 1	Liver-Ad Lib- Heterozygous knockout	Liver-Ad Lib- Heterozygous knockout	Liver-Ad Lib- Heterozygous knockout-replicate 1	2-5 months old	male	EFO	EFO_0001266	Heterozygous knockout  (SIRT1+/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139927 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139927 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139927	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139927_sample_table.txt norm	GSM1139927_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Heterozygous knockout  (SIRT1+/-)	Ad libitum diet
GSM1139926 1	Liver-Ad Lib- Homozygous knockout	Liver-Ad Lib- Homozygous knockout	Liver-Ad Lib- Homozygous knockout-replicate 1	2-5 months old	male	EFO	EFO_0001266	Homozygous knockout  (SIRT1-/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139926 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139926 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139926	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139926_sample_table.txt norm	GSM1139926_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Homozygous knockout  (SIRT1-/-)	Ad libitum diet
GSM1139925 1	Liver-Caloric Restriction- Heterozygous knockout	Liver-Caloric Restriction- Heterozygous knockout	Liver-Caloric Restriction- Heterozygous knockout-replicate 3	2-5 months old	male	EFO	EFO_0001266	Heterozygous knockout  (SIRT1+/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139925 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139925 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139925	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139925_sample_table.txt norm	GSM1139925_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Heterozygous knockout  (SIRT1+/-)	40% Caloric restricted diet
GSM1139924 1	Liver-Caloric Restriction- Heterozygous knockout	Liver-Caloric Restriction- Heterozygous knockout	Liver-Caloric Restriction- Heterozygous knockout-replicate 2	2-5 months old	male	EFO	EFO_0001266	Heterozygous knockout  (SIRT1+/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139924 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139924 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139924	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139924_sample_table.txt norm	GSM1139924_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Heterozygous knockout  (SIRT1+/-)	40% Caloric restricted diet
GSM1139923 1	Liver-Caloric Restriction- Wt	Liver-Caloric Restriction- Wt	Liver-Caloric Restriction- Wt-replcate 3	2-5 months old	male	EFO	EFO_0001266	Wild Type  (SIRT1+/+)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139923 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139923 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139923	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139923_sample_table.txt norm	GSM1139923_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Wild Type  (SIRT1+/+)	40% Caloric restricted diet
GSM1139922 1	Liver-Caloric Restriction- Heterozygous knockout	Liver-Caloric Restriction- Heterozygous knockout	Liver-Caloric Restriction- Heterozygous knockout-replicate 1	2-5 months old	male	EFO	EFO_0001266	Heterozygous knockout  (SIRT1+/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139922 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139922 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139922	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139922_sample_table.txt norm	GSM1139922_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Heterozygous knockout  (SIRT1+/-)	40% Caloric restricted diet
GSM1139921 1	Liver-Caloric Restriction- Homozygous knockout	Liver-Caloric Restriction- Homozygous knockout	Liver-Caloric Restriction- Homozygous knockout-replicate 3	2-5 months old	male	EFO	EFO_0001266	Homozygous knockout  (SIRT1-/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139921 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139921 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139921	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139921_sample_table.txt norm	GSM1139921_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Homozygous knockout  (SIRT1-/-)	40% Caloric restricted diet
GSM1139920 1	Liver-Caloric Restriction- Homozygous knockout	Liver-Caloric Restriction- Homozygous knockout	Liver-Caloric Restriction- Homozygous knockout-replicate 2	2-5 months old	male	EFO	EFO_0001266	Homozygous knockout  (SIRT1-/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139920 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139920 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139920	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139920_sample_table.txt norm	GSM1139920_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Homozygous knockout  (SIRT1-/-)	40% Caloric restricted diet
GSM1139919 1	Liver-Caloric Restriction- Homozygous knockout	Liver-Caloric Restriction- Homozygous knockout	Liver-Caloric Restriction- Homozygous knockout-replicate 1	2-5 months old	male	EFO	EFO_0001266	Homozygous knockout  (SIRT1-/-)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139919 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139919 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139919	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139919_sample_table.txt norm	GSM1139919_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Homozygous knockout  (SIRT1-/-)	40% Caloric restricted diet
GSM1139918 1	Liver-Caloric Restriction- Wt	Liver-Caloric Restriction- Wt	Liver-Caloric Restriction- Wt-replcate 2	2-5 months old	male	EFO	EFO_0001266	Wild Type  (SIRT1+/+)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139918 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139918 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139918	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139918_sample_table.txt norm	GSM1139918_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Wild Type  (SIRT1+/+)	40% Caloric restricted diet
GSM1139917 1	Liver-Caloric Restriction- Wt	Liver-Caloric Restriction- Wt	Liver-Caloric Restriction- Wt-replcate 1	2-5 months old	male	EFO	EFO_0001266	Wild Type  (SIRT1+/+)	Mus musculus	EFO	http://purl.obolibrary.org/obo/NCBITaxon_10090	C57BL/6J	EFO	EFO_0000606	P-GSE46895-2	ArrayExpress	P-GSE46895-3	ArrayExpress	P-GSE46895-4	ArrayExpress	GSM1139917 extract 1	total RNA	P-GSE46895-5	ArrayExpress	GSM1139917 LE 1	biotin	P-GSE46895-6	ArrayExpress	GSM1139917	A-MEXP-1174	ArrayExpress	array assay	P-GSE46895-1	ArrayExpress	P-GSE46895-7	ArrayExpress	GSM1139917_sample_table.txt norm	GSM1139917_sample_table.txt	ftp://ftp.ebi.ac.uk/pub/databases/microarray/data/experiment/GEOD/E-GEOD-46895/E-GEOD-46895.processed.1.zip	Wild Type  (SIRT1+/+)	40% Caloric restricted diet