Comment[ArrayExpressAccession]	E-GEOD-42882
MAGE-TAB Version	1.1					
Public Release Date	2013-01-10
Investigation Title	DNA methylation in the malignant transformation of meningiomas					
Comment[Submitted Name]	DNA methylation in the malignant transformation of meningiomas
Experiment Description	Genome wide DNA methylation profiling of malignant, atypical and benign meningiomas samples. The Illumina infinium HumanMethylation450 beadchip kit was used, which assayed 450,000 potential methylation sites. Bisulphite converted DNA from the 23 samples were hybridised to the Illumina Infinium 450 Human Methylation Beadchip.					
Term Source Name	ArrayExpress	EFO
Term Source File	http://www.ebi.ac.uk/arrayexpress/	http://www.ebi.ac.uk/efo/efo.owl				
Person Last Name	Gao	Gao	Wang			
Person First Name	Fan	Fan	Kai			
Person Email	gaofan83@hotmail.com					
Person Affiliation	USC					
Person Address	ZNI, USC, 1501 San Pablo St. ZNI 245, Los Angeles, California, USA					
Person Roles	submitter					
Protocol Name	P-GSE42882-1	P-GSE42882-5	P-GSE42882-4	P-GSE42882-2	P-GSE42882-3	P-GSE42882-6
Protocol Description	ID_REF =  VALUE = Average Beta (background subtracted)	Arrays were imaged using BeadArray Reader using standard recommended Illumina scanner setting	Bisulphite converted DNA was amplified, fragmented and hybridised to Illumina Infinium Human Methylation450 Beadchip using standard Illumina protocol.	Genomic DNA was extracted from meningiomas tissues using Qiagen DNeasy Kit according to standard instructions.	Standard Illumina Protocol	BeadStudio software v3.2
Protocol Type	bioassay_data_transformation	image_aquisition	hybridization	nucleic_acid_extraction	labeling	feature_extraction
Experimental Factor Name	SUBTYPE	TISSUE TYPE	SEX			
Experimental Factor Type	subtype	tissue type	sex			
Comment[SecondaryAccession]	GSE42882					
Comment[GEOReleaseDate]	2013-01-10					
Comment[ArrayExpressSubmissionDate]	2012-12-12					
Comment[GEOLastUpdateDate]	2013-01-18					
Comment[AEExperimentType]	methylation profiling by array					
Comment[AdditionalFile:Data1]	GSE42882_methylated_intensity.txt					
Comment[AdditionalFile:Data2]	GSE42882_p-values.txt					
Comment[AdditionalFile:Data3]	GSE42882_uncorrected_beta_values.txt					
Comment[AdditionalFile:Data4]	GSE42882_unmethylated_intensity.txt					
SDRF File	E-GEOD-42882.sdrf.txt