Investigation Title Transcription profiling of male and female human hypothalamus tissue Comment[Submitted Name] Sex Specific Transciption in Human Hypothalamus Experimental Design sex_design co-expression_design transcription profiling by array Experimental Design Term Source REF mo mo EFO Comment[ArrayExpressReleaseDate] 2007-07-24 Comment[SecondaryAccession] GSE1147 Comment[AEMIAMESCORE] 4 Comment[SecondaryAccession] GDS564 Comment[ArrayExpressAccession] E-GEOD-1147 Comment[MAGETAB TimeStamp_Version] 2010-07-22 04:07:26 Last Changed Rev: 13058 Experimental Factor Name sex Experimental Factor Type sex Experimental Factor Term Source REF Person Last Name Rozowsky Person First Name Joel Person Mid Initials Person Email rozowsky@csb.yale.edu Person Phone Person Fax Person Address Gerstein Lab, Molecular Biophysics & Biochemistry, Yale University, 266 Whitney Ave, Bass 437, New Haven, 06520, USA Person Affiliation Yale University Person Roles submitter Person Roles Term Source REF The MGED Ontology Quality Control Type Quality Control Term Source REF Replicate Type Replicate Term Source REF Normalization Type Normalization Term Source REF Date of Experiment Public Release Date 2007-07-24 PubMed ID 15177028 Publication DOI 15177028 Publication Author List Rinn JL, Rozowsky JS, Laurenzi IJ, Petersen PH, Zou K, Zhong W, Gerstein M, Snyder M Publication Title Major molecular differences between mammalian sexes are involved in drug metabolism and renal function Publication Status journal_article Publication Status Term Source REF The MGED Ontology Experiment Description Sex Specific Transciption in Human Hypothalamus between 7 male biological samples (2 technical replicates of each) and 5 female biological samples (2 technical replicates of 4 of these). Post-mordem human hypothalamus total RNA samples were obtained from Ambion (Austin, TX). All total RNA samples has an agilent ratio greater than 1 indicating there had been no degredation. The causes of death varied as well as the age at death, but averaged aproximately 70 years of age. The total RNA samples were labeled for hybridization onto the microarray according to affymetrix protocols listed at: http://keck.med.yale.edu/affymetrix/protocols Protocol Name Protocol Type Protocol Description Protocol Parameters Protocol Hardware Protocol Software Protocol Contact Protocol Term Source REF SDRF File E-GEOD-1147.sdrf.txt Term Source Name NCI_thesaurus mo The MGED Ontology ArrayExpress mo EFO The MGED Ontology Term Source File ncithesaurus.obo.alt http://mged.sourceforge.net/ontologies/MGEDontology.php http://mged.sourceforge.net/ontologies/MGEDontology.php http://www.ebi.ac.uk/arrayexpress http://mged.sourceforge.net/ontologies/MGEDontology.php http://www.ebi.ac.uk/efo/ http://mged.sourceforge.net/ontologies/MGEDontology.php Term Source Version Comment[AEExperimentType] transcription profiling by array