E-TABM-709 - Transcription profiling by array of mice with epileptic tolerance
Released on 22 May 2009, last updated on 4 June 2014
Microarray analysis was performed 24 hr after status epilepticus in mice that had received previously either siezure preconditioning (tolerance) or sham-preconditioning (injury). Transcriptional changes in the CA3 subfield of the hippocampus were analyzed using the Affymetric Mouse 430_2 Genechip.
transcription profiling by array, cell process, co-expression, compound treatment, in vivo, injury, is expressed, stimulus or stress
Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Jimenez-Mateos EM, Hatazaki S, Johnson MB, Bellver-Estelles C, Mouri G, Bonner C, Prehn JH, Meller R, Simon RP, Henshall DC. , Europe PMC 18804535