E-TABM-53 - Transcription profiling of human nephroblastoma

Status
Released on 30 July 2007, last updated on 2 May 2014
Organism
Homo sapiens
Samples (69)
Array (1)
Protocols (7)
Description
A ""Cartes d'Identite des Tumeurs"" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). 73 samples (60 tumoral, 6 normal kidneys (NK), 3 fetal kidneys (FK) and 4 cell lines (L)), hybridized on Affymetrix HG-U133A GeneChips.Tumor classification based on a characterization of WT1 and Betacatenin. Identification of major differences between two categories of Wilms' Tumors defined according to WT1 and CTNNB1 genomic and expression features. First large scale study based on post-chemotherapy resected tumors, according to the SIOP protocoles.
Experiment types
transcription profiling by array, clinical history, disease state
Contacts
Fabien Petel <PetelF@ligue-cancer.net>, Aurélien de Reyniès, Catherine Patte, Claudine Junien, Cécile Jeanpierre, David Rickman, Dominique Berrebi, Francis Jaubert, Funda Vilmaz, Gudrun Schleichmacher, Judith Landman-Parker, Julie Leclerc, Liliane Boccon-Gibod, Marie Corbin, Marine Faussillon, Monique Fabre
Citation
WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries?. Corbin M, de Reynies A, Rickman DS, Berrebi D, Boccon-Gibod L, Cohen-Gogo S, Fabre M, Jaubert F, Faussillon M, Yilmaz F, Sarnacki S, Landman-Parker J, Patte C, Schleiermacher G, Antignac C, Jeanpierre C.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-TABM-53.idf.txt
Sample and data relationshipE-TABM-53.sdrf.txt
Raw data (2)E-TABM-53.raw.1.zip, E-TABM-53.raw.2.zip
Processed data (1)E-TABM-53.processed.1.zip
Array designA-AFFY-33.adf.txt
R ExpressionSetE-TABM-53.eSet.r
Links