E-TABM-310 - Transcription profiling of wild type, Atf3(-/-), Ticam1(-/-), MyD88(-/-) and CREM(-/-) murine bone marrow-derived macrophages stimulated with purified Toll-like receptor agonists after 0-48 hours

Status
Released on 26 March 2008, last updated on 22 August 2016
Organism
Mus musculus
Samples (216)
Array (1)
Protocols (7)
Description
Time course data from purified Toll-like receptor agonist-stimulated wild_type and knockout murine bone marrow-derived macrophages were collected to investigate the transcriptional network in TLR-activated macrophages.
Experiment types
transcription profiling by array, co-expression, compound treatment, stimulated type, time series
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Citations
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Litvak V, Ratushny AV, Lampano AE, Schmitz F, Huang AC, Raman A, Rust AG, Bergthaler A, Aitchison JD, Aderem A. , Europe PMC 22982991
Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics. Ramsey SA, Klemm SL, Zak DE, Kennedy KA, Thorsson V, Li B, Gilchrist M, Gold ES, Johnson CD, Litvak V, Navarro G, Roach JC, Rosenberger CM, Rust AG, Yudkovsky N, Aderem A, Shmulevich I. , Europe PMC 18369420
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