E-TABM-137 - Transcription profiling of lung tissue from transcription-coupled repair-deficient (Csb-/-) and wild type mice in response to ozone

Status
Submitted on 18 August 2006, released on 13 November 2006, last updated on 2 May 2014
Organism
Mus musculus
Samples (23)
Array (1)
Protocols (8)
Description
We investigated whether transcription-coupled repair deficient mice (Cockayne syndrome B knockout mice (Csb-/-)), known to be sensitive to oxidative stressors, have a different response to ozone than its repair-proficient control, Csb heterozygote (Csb+/-) mice.
Experiment types
transcription profiling by array, compound treatment, individual genetic characteristics, reference
Contacts
Citation
Ozone induces clear cellular and molecular responses in the mouse lung independently of the transcription-coupled repair status. Ingeborg M. Kooter, Jeroen L.A. Pennings, Paul H. B. Fokkens, Daan L.A. C. Leseman, A. John F. Boere, Miriam E. Gerlofs-Nijland, Flemming R. Cassee, Johanna A. C. Schalk, Tom J. H. Orzechowski, Mirjam M. Schaap, Timo M. Breit, Jan A.M.A. Dormans, Conny T.M. van Oostrom, Annemieke de Vries, Harry van Steeg. J Appl Phys  (2006)
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-TABM-137.idf.txt
Sample and data relationshipE-TABM-137.sdrf.txt
Raw data (1)E-TABM-137.raw.1.zip
Processed data (1)E-TABM-137.processed.1.zip
Array designA-MEXP-542.adf.txt
Links