E-SMDB-1398 - Transcription profiling of C. elegans with activated let-60 Ras
Released on 13 July 2005, submitted on 14 July 2005, last updated on 27 March 2012
In Caenorhabditis elegans, let-60 Ras controls many cellular processes, such as differentiation of vulval epithelial cells, function of chemosensory neurons, and meiotic progression in the germ line. Although much is known about the let-60 Ras signaling pathway, relatively little is understood about the target genes induced by let-60 Ras signaling that carry out terminal effector functions leading to morphological change. We have used DNA microarrays to identify 708 genes that change expression in response to activated let-60 Ras.
transcription profiling by array, unknown experiment type
Downstream Targets of let-60 Ras in Caenorhabditis elegans. Romagnolo B, Jiang M, Kiraly M, Breton C, Begley R, Wang J, Lund J, Kim SK. Dev Biol 247:127-36 (2002-06-21), Europe PMC 12074557