E-MTAB-34 - Strain abundance assay of barcoded heterozygous and homozygous yeast single gene deletion strains exposed to 87 psychoactive drugs

Status
Released on 7 July 2008, last updated on 3 June 2014
Organism
Saccharomyces cerevisiae
Samples (105)
Array (1)
Protocols (4)
Description
To profile off-target effects of psychoactive drugs, 87 genome-wide drug fitness assays (of which 5 were performed in duplicate) and 18 genome-wide control experiments were performed in Saccharomyces cerevisiae. Heterozygous and homozygous yeast single gene deletion strains from the BY collection of the Saccharomyces cerevisiae genome deletion consortium were used.
Experiment types
RNAi profiling by array, compound treatment, growth condition, in vivo, strain abundance
Contact
Citation
Off-Target Effects of Psychoactive Drugs Revealed by Genome-wide Assays in Yeast. Elke Ericson, Marinella Gebbia, Lawrence E. Heisler, Jan Wildenhain, Myke Tyers, Guri Giaever, Corey Nislow.
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MTAB-34.idf.txt
Sample and data relationshipE-MTAB-34.sdrf.txt
Raw data (1)E-MTAB-34.raw.1.zip
Processed data (1)E-MTAB-34.processed.1.zip
Array designA-AFFY-118.adf.txt
Links