E-MTAB-2431 - sponge development
Last updated on 24 March 2014, released on 1 May 2014
In order to compare sponge and eumetazoan (higher animal) body plans, we identified and studied expression of a broad range of eumetazoan developmental regulatory genes in Sycon ciliatum (Calcispongiae). In this species, embryonic development is semi-synchronous within a population, synchronous within individuals, and oocytes and embryos occupy a significant fraction of the volume of the sponges during the reproductive period. RNASeq libraries representing non-reproductive (somatic) tissue slices along the body axis, as well as oocytes, embryos and free swimming larvae were generated from material obtained by sampling throughout the life cycle.
RNA-seq of coding RNA, all pairs, co-expression, development or differentiation design
Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes. Sofia A. V. Fortunato, Marcin Adamski, Olivia Mendivil Ramos, Sven Leininger, Jing Liu, David E. K. Ferrier. Nature 514:620-623 (2014)
Developmental gene expression provides clues to relationships between sponge and eumetazoan body plans. Leininger S, Adamski M, Bergum B, Guder C, Liu J, Laplante M, Bråte J, Hoffmann F, Fortunato S, Jordal S, Rapp HT, Adamska M. Nature Communications 5 (2014), Europe PMC 24844197