E-MTAB-2334 - Transcription profiling by array of mouse oesophageal epithelium basal cells comparing DNMaml expressing cells versus controls

Status
Released on 8 April 2014, last updated on 3 June 2014
Organism
Mus musculus
Samples (10)
Array (1)
Protocols (8)
Description
Multiple cancers may arise from within a clonal region of preneoplastic epithelium, a phenomenon termed ‘field change’. However, it is not known how field change develops. We investigate this question and analyse the behavior of scattered single esophageal epithelial progenitor cells expressing a mutation that inhibits the Notch signaling pathway (Dominant negative Maml).
Experiment types
transcription profiling by array, co-expression, development or differentiation design, in vivo
Contact
Citation
Differentiation imbalance in single esophageal progenitor cells causes clonal immortalization and field change. Maria P. Alcolea, Philip Greulich, Agnieszka Wabik, Benjamin D. Simons,Philip H. Jones.
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MTAB-2334.idf.txt
Sample and data relationshipE-MTAB-2334.sdrf.txt
Raw data (1)E-MTAB-2334.raw.1.zip
Processed data (2)E-MTAB-2334.processed.1.zip, E-MTAB-2334.processed.2.zip
Array designA-MEXP-1175.adf.txt
Links