E-MTAB-2127 - Comparison of gene expression in S.aureus strains with different triclosan sensitivities
Last updated on 3 June 2014, released on 5 July 2014
Difference in sensitivity for the biocide triclosan has been observed in S.aureus. This may rely on changes in gene expression between strains. The present project investigates such changes in in vivo generated mutants and in clinical isolates. A collection of normalised data matrices for this study, together with supporting information, have been provided as additional files: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-2127/E-MTAB-2127.additional.1.zip .
transcription profiling by array, strain or line design
Mutations in the fabI promoter often associate with alternative mechanisms of triclosan resistance. Denis Grandgirard, Leonardo Furi, Maria Laura Ciusa, Lucilla Baldassarri, Daniel Knigh, Ian Morrissey, Carlo R.