E-MTAB-1943 - Genome-wide expression analysis of Schwann cells upon Wnt loss-of-function and gain-of-function treatments

Status
Released on 25 October 2013, last updated on 3 June 2014
Organism
mus musculus
Samples (19)
Array (1)
Protocols (7)
Description
Analysis of genes regulated by canonical Wnt signaling in the murine primary Schwann cells. Total RNA from b-catenin fl/fl Schwann cells, after introducing loss-of-function mutations with HTN-cre, or mimicking gain-of-function mutations with Chir98014 or Wnt3a-treatments, was compared to the respective controls.
Experiment types
transcription profiling by array, co-expression, compound treatment, development or differentiation, genetic modification, in vitro
Contacts
Citations
Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development. Grigoryan T, Stein S, Qi J, Wende H, Garratt AN, Nave KA, Birchmeier C, Birchmeier W. :18174-18179 (2013), Europe PMC 24151333
Wnt/Rspondin/beta-catenin signals control axonal sorting and lineage progression in Schwann cell development. Tamara Grigoryan , Simone Stein , Jingjing Qi , Hagen Wende , Alistair N. Garratt , Klaus-Armin Nave , Carmen Birchmeier , Walter Birchmeier .
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-1943.idf.txt
Sample and data relationshipE-MTAB-1943.sdrf.txt
Raw data (1)E-MTAB-1943.raw.1.zip
Processed data (1)E-MTAB-1943.processed.1.zip
Array designA-MEXP-1174.adf.txt
Links