E-MTAB-1939 - Comparative genomic hybridization by array of non-small cell lung cancer (NSCLC) cell lines treated with deoxyazacitidine or trichostatin A against untreated samples to identify cancer specific methylation

Status
Released on 10 December 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (16)
Array (1)
Protocols (9)
Description
Deoxyazacitidine is used to elicit expression of cancer specific methylated genes. Non-small cell lung cancer cell lines are treated with either deoxyazacitidine or trichostatin A to identify cancer specific methylation
Experiment types
comparative genomic hybridization by array, comparative genome hybridization, compound treatment, in vitro
Contacts
Citation
Functional Identification of Cancer-Specific Methylation of CDO1, HOXA9, and TAC1 for the Diagnosis of Lung Cancer. Wrangle J, Machida EO, Danilova L, Hulbert A, Franco N, Zhang W, Glockner S, Tessema M, Van Neste L, Easwaran H, Schuebel KE, Licchesi J, Hooker CM, Ahuja N, Amano J, Belinsky SA, Baylin SB, Herman JG, Brock MV. Clin Cancer Res  (2014), Europe PMC 24486589
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MTAB-1939.idf.txt
Sample and data relationshipE-MTAB-1939.sdrf.txt
Raw data (2)E-MTAB-1939.raw.1.zip, E-MTAB-1939.raw.2.zip
Array designA-AGIL-28.adf.txt
Links