E-MTAB-1922 - Transcription profiling by array of Porphyromonas gingivalis infection on gene expression in human aortic smooth muscle cells (AoSMCs) and its relation to cellular function

Status
Released on 17 November 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (8)
Array (1)
Protocols (7)
Description
Porphyromonas gingivalis is a gram-negative bacterium that causes destructive chronic periodontitis. In addition, this bacterium is also involved in the development of cardiovascular disease. The aim of this study was to investigate the effects of P. gingivalis infection on gene and protein expression in human aortic smooth muscle cells (AoSMCs) and its relation to cellular function.
Experiment types
transcription profiling by array, co-expression, stimulus or stress design
Contact
Citations
The periodontal pathogen Porphyromonas gingivalis changes the gene expression in vascular smooth muscle cells involving the TGFbeta/Notch signalling pathway and increased cell proliferation. Boxi Zhang, Ali Ateia Elmabsout, Hazem Khalaf, Vladimir T Basic, Kartheyaene Jayaprakash, Robert Kruse, Torbjörn Bengtsson and Allan Sirsjö. BMC Genomics 14:77 (2013), Europe PMC 24209892
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-1922.idf.txt
Sample and data relationshipE-MTAB-1922.sdrf.txt
Raw data (1)E-MTAB-1922.raw.1.zip
Processed data (1)E-MTAB-1922.processed.1.zip
Array designA-AGIL-28.adf.txt
Links