E-MTAB-1903 - Transcription profiling by array of a field collection of Anopheles gambiae M molecular form compared to two laboratory strains and to a wild caught field strain to investigate their differences in insecticide resistance
Released on 3 December 2013, last updated on 3 June 2014
Transcription profiles of a field collection of Anopheles gambiae M molecular form (i.e. Anopheles coluzzii) from a population from Cote d'Ivoire (West Africa) were compared to two laboratory strains and to a wild caught field strain (all carbamate insecticide susceptible) to investigate their differences in insecticide resistance. Both carbamate-exposed and carbamate-unexposed Cote d'Ivoire samples were compared to each susceptible strain, and also directly to one another (i.e. exposed vs. unexposed).
transcription profiling by array, co-expression, dye swap design, strain or line design
CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae. Constant V. Edi, Luc Djogbénou, Adam M. Jenkins, Kimberly Regna, Marc A. T. Muskavitch, Christopher M. Jones, Guillaume K. Kétoh, Benjamin G. Koudou, Martin J. Donnelly, Hilary Ranson, David Weetman.