E-MTAB-1667 - RNA-seq of coding RNA from Mycobacterium tuberculosis H37Rv overexpressing HigB compared to the empty vector control strain to investigate the role of the HigB toxin

Status
Last updated on 16 September 2013, released on 16 September 2013
Organism
Mycobacterium tuberculosis
Samples (2)
Protocols (4)
Description
In this study RNA-seq analysis of M. tuberculosis H37Rv overexpressing HigB compared to the empty vector control strain has been performed in order to investigate the role of the HigB toxin
Experiment types
RNA-seq of coding RNA, co-expression, genetic modification design
Contact
Citation
Induced ectopic expression of HigB toxin in Mycobacterium tuberculosis results in growth inhibition, reduced abundance of a subset of mRNAs and cleavage of tmRNA. Schuessler, D.L., Cortes, T*.*, Fivian-Hughes, A.S., Lougheed, K.E., Harvey, E., Buxton, R.S., Davis, E.O., Young, D.B. Mol Microbiol  (2013), Europe PMC 23927792
MINSEQE
Exp. designProtocolsFactorsProcessedSeq. reads
Files
Investigation descriptionE-MTAB-1667.idf.txt
Sample and data relationshipE-MTAB-1667.sdrf.txt
Links