E-MTAB-1613 - RNA-seq of epidermal sheets of epidermal sheet-specific Evi-K14-Cre knockout mice and wild-type controls
Released on 24 July 2013, last updated on 3 May 2014
Evi/Wls is an essential Wnt secretion factor and important for tissue homeostasis. In the skin Wnt signaling plays an important role in hair follicle formation and maintenance. The aim of the present study is to compare the gene expression profile of Evi/Wls knockout epidermal sheets with wild-type control skin.
RNA-seq of coding RNA, co-expression, in vivo, organism part comparison
Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis. Iris Augustin; Julia Gross; Daniel Baumann; Claudia Korn; Grainne Kerr; Tamara Grigoryan; Cornelia Mauch; Walter Birchmeier; Michael Boutros. J Exp Med 210(9):1761 (2013), Europe PMC 23918954