E-MTAB-1584 - Genotyping by array of human BIN-67 small cell ovarian carcinoma to investigate genomic stability

Status
Released on 24 September 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (1)
Array (1)
Protocols (6)
Description
The biology of small cell ovarian carcinoma of the hypercalcemic type (SCCOHT), which is a rare and aggressive form of ovarian cancer, is poorly understood. Tumourigenicity, in vitro growth characteristics, genetic and genomic anomalies, and sensitivity to standard and novel chemotherapeutic treatments were investigated in the unique SCCOHT cell line, BIN-67, to provide further insight in the biology of this rare type of ovarian cancer. Chromosomal anomalies in BIN-67 cells were inferred using the Infinium? genotyping technology with the HumanHap300-Duo Genotyping BeadChip (Illumina, San Diego, CA, USA). This BeadChip contains about 318,000 genetic markers within approximately a 5 kb median SNP spacing. Genotyping and imaging using BeadStudio Data Analysis software (Illumina, San Diego, CA, USA) were performed at the McGill University and Genome Quebec Innovation Centre (Montreal, QC).
Experiment types
genotyping by array, disease state, genotyping, in vitro
Contacts
Citation
Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics. Gamwell LF, Gambaro K, Merziotis M, Crane C, Arcand SL, Bourada V, Davis C, Squire JA, Huntsman DG, Tonin PN, Vanderhyden BC.
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MTAB-1584.idf.txt
Sample and data relationshipE-MTAB-1584.sdrf.txt
Raw data (1)E-MTAB-1584.raw.1.zip
Processed data (1)E-MTAB-1584.processed.1.zip
Array designA-GEOD-6980.adf.txt
Links