E-MTAB-1538 - RNA-seq of adult C57BL/6J mice injected with 350mg/kg of acetaminophen vs control to investigate drug associated adverse effects
Last updated on 7 March 2013, released on 8 March 2013
Comprehensive cataloging of cell-free circulating RNAs using next generation sequencing technology may open a window to assess drug associated adverse effects at the systems level. To explore this potential, we conducted an RNA profiling study using the well-characterized acetaminophen overdose mouse model on liver and plasma with next generation sequencing platforms.
RNA-seq of coding RNA, time series
The Spectrum of Circulating RNA: A Window Into Systems Toxicology. Kai Wang, Yue Yuan, Hong Li, Ji-Hoon Cho, David Huang, Li Gray, Shizhen Qin and David J. Galas.