E-MTAB-1538 - RNA-seq of adult C57BL/6J mice injected with 350mg/kg of acetaminophen vs control to investigate drug associated adverse effects

Status
Last updated on 7 March 2013, released on 8 March 2013
Organism
Mus musculus
Samples (5)
Protocols (5)
Description
Comprehensive cataloging of cell-free circulating RNAs using next generation sequencing technology may open a window to assess drug associated adverse effects at the systems level. To explore this potential, we conducted an RNA profiling study using the well-characterized acetaminophen overdose mouse model on liver and plasma with next generation sequencing platforms.
Experiment types
RNA-seq of coding RNA, time series
Contact
Citation
The Spectrum of Circulating RNA: A Window Into Systems Toxicology. Kai Wang, Yue Yuan, Hong Li, Ji-Hoon Cho, David Huang, Li Gray, Shizhen Qin and David J. Galas.
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-1538.idf.txt
Sample and data relationshipE-MTAB-1538.sdrf.txt
Links