E-MTAB-1511 - ChIP-seq of human, chimpanzee, gorilla, orang-utan, macaque, baboon and marmoset using lymphoblastoid cell lines to investigate the evolutionary comparison of CTCF and YY1 binding
Released on 20 November 2013, last updated on 3 May 2014
Gorilla gorilla gorilla, Homo sapiens, Macaca mulatta, Mus musculus, Pan troglodytes , Papio hamadryas, Pongo pygmaeus pygmaeus, Sanguinus oedipus
We performed an evolutionary comparison of the binding of the TF CTCF in human, chimpanzee, gorilla, orang-utan, macaque, baboon and marmoset using lymphoblastoid cell lines (LCLs). We also probes YY1 binding in human, chimpanzee, orang-utan and baboon LCLs as well as human and mouse liver.
ChIP-seq, ChiP-seq, in vitro, in vivo, replicate, species
Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes. Schwalie PC, Ward MC, Cain CE, Faure AJ, Gilad Y, Odom DT, Flicek P. Genome Biology 14(12):R148 (2013), Europe PMC 24380390