E-MTAB-1511 - ChIP-seq of human, chimpanzee, gorilla, orang-utan, macaque, baboon and marmoset using lymphoblastoid cell lines to investigate the evolutionary comparison of CTCF and YY1 binding
Released on 20 November 2013, last updated on 14 February 2014
Gorilla gorilla gorilla, Homo sapiens, Macaca mulatta, Mus musculus, Pan troglodytes , Papio hamadryas, Pongo pygmaeus pygmaeus, Sanguinus oedipus
We performed an evolutionary comparison of the binding of the TF CTCF in human, chimpanzee, gorilla, orang-utan, macaque, baboon and marmoset using lymphoblastoid cell lines (LCLs). We also probes YY1 binding in human, chimpanzee, orang-utan and baboon LCLs as well as human and mouse liver.
ChIP-seq, ChiP-seq, in vitro, in vivo, replicate, species
Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes. Schwalie PC, Ward MC, Cain CE, Faure AJ, Gilad Y, Odom DT, Flicek P. Genome Biology 14(12):R148 (2013), Europe PMC 24380390