E-MTAB-1491 - Transcription profiling by array of human HuS-E/2 2D and 3D cultered cells to identify novel factors which support HCV proliferation

Status
Released on 10 December 2013, last updated on 3 May 2014
Organism
Homo sapiens
Samples (3)
Array (1)
Protocols (8)
Description
HCV proliferation is closely related to three-dimentional cellular condition. In case of blood-borne (bb) HCV culture in HuS-E2 cells, bbHCV was reproduced only from 3D-cultured cells in hollow fibers. Thus, in order to identify novel factors which support HCV proliferation under three-dimentional condition, we compared gene expression profile between 2D- and 3D-cultured HuS-E/2 cells with 3D-gene Human oligo chip 25k (Toray, Tokyo, Japan).
Experiment types
transcription profiling by array, cell type comparison, co-expression, in vitro
Contact
Citation
Thromboxane A2 synthase inhibitors prevent production of infectious hepatitis C virus in mice with humanized livers. Abe Y, Aly HH, Hiraga N, Imamura M, Wakita T, Shimotohno K, Chayama K, Hijikata M . Gastroenterology  (2013), Europe PMC 23684750
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MTAB-1491.idf.txt
Sample and data relationshipE-MTAB-1491.sdrf.txt
Raw data (1)E-MTAB-1491.raw.1.zip
Processed data (2)E-MTAB-1491.processed.1.zip, E-MTAB-1491.processed.2.zip
Array designA-GEOD-5639.adf.txt
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