E-MTAB-1491 - Transcription profiling by array of human HuS-E/2 2D and 3D cultered cells to identify novel factors which support HCV proliferation

Status
Released on 10 December 2013, last updated on 3 May 2014
Organism
Homo sapiens
Samples (3)
Array (1)
Protocols (8)
Description
HCV proliferation is closely related to three-dimentional cellular condition. In case of blood-borne (bb) HCV culture in HuS-E2 cells, bbHCV was reproduced only from 3D-cultured cells in hollow fibers. Thus, in order to identify novel factors which support HCV proliferation under three-dimentional condition, we compared gene expression profile between 2D- and 3D-cultured HuS-E/2 cells with 3D-gene Human oligo chip 25k (Toray, Tokyo, Japan).
Experiment types
transcription profiling by array, cell type comparison, co-expression, in vitro
Contact
Citation
Thromboxane A2 synthase inhibitors prevent production of infectious hepatitis C virus in mice with humanized livers. Abe Y, Aly HH, Hiraga N, Imamura M, Wakita T, Shimotohno K, Chayama K, Hijikata M. Gastroenterology  (2013), Europe PMC 23684750
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-1491.idf.txt
Sample and data relationshipE-MTAB-1491.sdrf.txt
Raw data (1)E-MTAB-1491.raw.1.zip
Processed data (2)E-MTAB-1491.processed.1.zip, E-MTAB-1491.processed.2.zip
Array designA-GEOD-5639.adf.txt
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