E-MTAB-1471 - Transcription profiling by array of human prostate cell lines to investigate the role of p63 and ZEB1 trancription factors in epithelial to mesenchymal transition
Submitted on 11 December 2012, released on 17 March 2013, last updated on 3 May 2014
In this experiment we investigated the role of p63 and ZEB1 trancription factors in epithelial to mesenchymal transition, in a human prostate cell culture. The influence of TFs was studied by a gain and loss of function approach.
transcription profiling by array, genetic modification design
Pawel Roger Sztromwasser <email@example.com>, Anne R. Oyan, Biaoyang Lin, David Micklem, Hallvard Haugen, James Lorens, Jan Margrete Olsen, Jie Liu, Kari R. Rostad, Karl-Henning Kalland, Lisha Li, Margrete B. Hellem, Varda Rotter, Xisong Ke
p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model. Olsen JR, Oyan AM, Rostad K, Hellem MR, Liu J, Li L, Micklem DR, Haugen H, Lorens JB, Rotter V, Ke XS, Lin B, Kalland KH. PLoS One 8(5):e62547 (2013), Europe PMC 23658742