E-MTAB-1422 - Transcription profiling by array of human precusor B cell subsets from children and adults

Status
Released on 1 July 2013, last updated on 24 July 2013
Organism
Homo sapiens
Samples (39)
Array (1)
Protocols (5)
Description
Through differentiation-stage dependent analysis and pair wise comparisons between children and adults of 5 precursor B cell subsets, we identified several mechanisms that suggest tighter checkpoint control in adult precursor B cells.
Experiment types
transcription profiling by array, all pairs, co-expression, development or differentiation
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Citation
Increased ID2 Levels in Adult Precursor B Cells as Compared with Children Is Associated with Impaired Ig Locus Contraction and Decreased Bone Marrow Output. Kristin Jensen; Magdalena B. Rother; Berit Sletbakk Brusletto; Ole K. Olstad; Hans Christian Dalsbotten Aass; Menno C. van Zelm; Peter Kierulf; Kaare M. Gautvik. J Immunol 191(3):1210 (2013), Europe PMC 23825313
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