E-MTAB-1298 - Methylation profiling by array of human oral squamous cell carcinoma samples against matched normal oral mucosa samples from the same cohort of patients

Status
Released on 2 August 2013, last updated on 3 May 2014
Organism
Homo sapiens
Samples (88)
Array (1)
Protocols (5)
Description
This study aims to compare the DNA methylome across a large cohort of oral squamous cell carcinoma and matched normal samples. DNA from 44 OSCCs and paired normal mucosa were analysed using Illumina GoldenGate methylation array. This data was correlated with extracapsular spread (extracapsular spread), Human Papilloma Virus (HPV) status, recurrence and 5-year survival.
Experiment types
methylation profiling by array, all pairs, binding site identification, disease state
Contact
Citation
The epigenetic landscape of oral squamous cell carcinoma. P V Jithesh, J M Risk, A G Schache, J Dhanda, B Lane, T Liloglou and R J Shaw. Br J Cancer 108:370-379
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MTAB-1298.idf.txt
Sample and data relationshipE-MTAB-1298.sdrf.txt
Raw data (1)E-MTAB-1298.raw.1.zip
Array designA-GEOD-9183.adf.txt
Links