E-MTAB-1281 - Transcription profiling by array of Paneth cells and whole ileum from human Crohn's disease patient ileo-colic resection tissue
Released on 3 January 2014, last updated on 3 May 2014
Transcriptional profiling of microscopically laser dissected Paneth cells and whole thickness ileum tissue from the proximal margins of archived formalin-fixed, paraffin-embedded ileo-colic resection samples.
transcription profiling by array, cell type comparison, co-expression, in vitro, organism part comparison
Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohns disease. Vandussen KL, Liu TC, Li D, Towfic F, Modiano N, Winter R, Haritunians T, Taylor KD, Dhall D, Targan SR, Xavier RJ, McGovern DP, Stappenbeck TS . Gastroenterology 146(1):200-209 (2014), Europe PMC 24076061