E-MTAB-127 - Transcription profiling of the islets from Pdx1+/- mice compared to islets isolated from Pdx1 +/+ littermates

Status
Released on 2 December 2009, last updated on 3 June 2014
Organism
Mus musculus
Samples (6)
Array (1)
Protocols (7)
Description
The aim of this experiment was to use global gene expression profiling to identify genes that are differentially expressed in the islets from Pdx1+/- mice compared to islets isolated from Pdx1 +/+ littermates. The Pdx1 null mutation consists of a nuclear targeted _-galactosidase cassette fused in-frame with the N terminus of PDX-1.
Experiment types
transcription profiling by array, co-expression, dye swap, genetic modification
Contacts
Citation
Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress. Sachdeva MM, Claiborn KC, Khoo C, Yang J, Groff DN, Mirmira RG, Stoffers DA. Proc Natl Acad Sci U S A. 106(45):19090-5 (2009)
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-127.idf.txt
Sample and data relationshipE-MTAB-127.sdrf.txt
Raw data (1)E-MTAB-127.raw.1.zip
Processed data (1)E-MTAB-127.processed.1.zip
Array designA-CBIL-10.adf.txt
R ExpressionSetE-MTAB-127.eSet.r
Links