E-MTAB-1192 - Transcription profiling by array of mouse wild-type and Insulin receptor (InsR)/Igf1 receptor (Igf1R) double knockout mutant Sertoli cells from testis at embryonic day E17.5 and Postnatal day 5

Status
Last updated on 29 October 2012, released on 9 March 2013
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (6)
Description
we performed the analysis of SOX9-GFP+ cells purified from mouse embryonic testis at embryonic day E17.5 and Postnatal day 5 and analyzed the effect of the deletion of the Insulin receptor (InsR) and Igf1 receptor (Igf1R) by comparing double mutant and control SOX9+ Sertoli cells
Experiment types
transcription profiling by array, genetic modification
Contact
Citation
An essential role for insulin and IGF1 receptors in regulating Sertoli cells proliferation, testis size and FSH action in mice. Jean-Luc Pitetti*, Pierre Calvel*, Marilena D. Papaioannou*, Florence Aubry?, Christopher Cederroth*, Fran?oise Urner3, Betty Fumel?, Michel Crausaz3, Pedro Luis Herrera*, Fran?ois Pralong2, Marc Germond3, Florian Guillou?, Bernard J?gou? and Serge Nef*??.
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MTAB-1192.idf.txt
Sample and data relationshipE-MTAB-1192.sdrf.txt
Raw data (1)E-MTAB-1192.raw.1.zip
Processed data (1)E-MTAB-1192.processed.1.zip
Array designA-AFFY-45.adf.txt
Links