E-MTAB-1192 - Transcriptional profiling by array of mouse wild-type and Insulin receptor (InsR)/Igf1 receptor (Igf1R) double knockout mutant Sertoli cells from testis at embryonic day E17.5 and Postnatal day 5

Status
Released on 9 March 2013, last updated on 23 October 2015
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (6)
Description
we performed the analysis of SOX9-GFP+ cells purified from mouse embryonic testis at embryonic day E17.5 and Postnatal day 5 and analyzed the effect of the deletion of the Insulin receptor (InsR) and Igf1 receptor (Igf1R) by comparing double mutant and control SOX9+ Sertoli cells
Experiment types
transcription profiling by array, genetic modification
Contact
Citation
An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice. Pitetti JL, Calvel P, Zimmermann C, Conne B, Papaioannou MD, Aubry F, Cederroth CR, Urner F, Fumel B, Crausaz M, Docquier M, Herrera PL, Pralong F, Germond M, Guillou F, Jégou B, Nef S. , Europe PMC 23518924
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-1192.idf.txt
Sample and data relationshipE-MTAB-1192.sdrf.txt
Raw data (1)E-MTAB-1192.raw.1.zip
Array designA-AFFY-45.adf.txt
Links