E-MTAB-1048 - Transcription profiling by array of liver, soleus muscle and white adipose tissue from Goto-Kakizaki and Brown Norway rats and 24 derived congenic strains
Released on 20 January 2014, last updated on 3 May 2014
Expression analysis was carried out in Goto-Kakizaki (GK), Brown Norway (BN) and 24 derived congenic strains using the Illumina RatRef-12 microarray. Each congenic line contains an introgression of a single fragment of the GK strain in the background of the BN recipient strain or vice versa. The resulting lines were fixed by imbreeding. The sizes of the introgressed fragments vary from almost a complete chromosome (consomic) to smaller fragments and some of the fragments overlap. To investigate genetic control of gene expression by the introgressed fragments, we performed transcriptional profiling of liver, soleus muscle and white adipose tissue in 6 months old rats.
transcription profiling by array, co-expression, replicate, strain or line
Genetic control of differential acetylation in diabetic rats. Kaisaki PJ, Otto GW, McGouran JF, Toubal A, Argoud K, Waller-Evans H, Finlay C, Caldérari S, Bihoreau MT, Kessler BM, Gauguier D, Mott R. PLoS One 9(4):e94555 (2014), Europe PMC 24743600