E-MIMR-3 - Transcription profiling of rat neonatal ventricular myocytes

Status
Released on 1 October 2006, last updated on 3 May 2014
Organism
Rattus norvegicus
Samples (12)
Arrays (2)
Protocols (113)
Description
Title: Regulation of gene expression through mitogen-activated protein kinase cascades in cardiac myocytes.
Description: The aim of this study is to identify the changes in gene expression induced in rat neonatal
ventricular myocytes, a well-established cell culture model, by endothelin-1,
a known hypertrophic agonist, and to determine which of the changes are
mediated through the ERK cascade. This continues TKACs previous study of the
effects of oxidative stress, which induces cardiac myocyte apoptosis.
Experiment types
transcription profiling by array, compound treatment, time series
Contacts
Citations
Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes. Cullingford TE, Markou T, Fuller SJ, Giraldo A, Pikkarainen S, Zoumpoulidou G, Alsafi A, Ekere C, Kemp TJ, Dennis JL, Game L, Sugden PH, Clerk A. :R32 (2008), Europe PMC 18275597
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MIMR-3.idf.txt
Sample and data relationshipE-MIMR-3.sdrf.txt
Processed data (1)E-MIMR-3.processed.1.zip
Array designsA-AFFY-18.adf.txt, A-AFFY-43.adf.txt
Links