E-MIMR-3 - Transcription profiling of rat neonatal ventricular myocytes
Released on 1 October 2006, last updated on 3 May 2014
Title: Regulation of gene expression through mitogen-activated protein kinase cascades in cardiac myocytes.
Description: The aim of this study is to identify the changes in gene expression induced in rat neonatal
ventricular myocytes, a well-established cell culture model, by endothelin-1,
a known hypertrophic agonist, and to determine which of the changes are
mediated through the ERK cascade. This continues TKACs previous study of the
effects of oxidative stress, which induces cardiac myocyte apoptosis.
transcription profiling by array, compound treatment, time series