E-MEXP-948 - Transcription profiling by array of rat prefrontal cortex after treatment with methamphetamine

Status
Released on 4 January 2007, last updated on 2 May 2014
Organism
Rattus norvegicus
Samples (30)
Array (1)
Protocols (6)
Description
To gain a better understanding of the mechanisms associated with the differences in the individual response to METH and thereby, further develop a list of candidate genes and pathways of possible relevance to human stimulant dependence, mania and psychosis, we conducted the present study. Rats were treated acutely with either METH or saline and their behavior measured for 3 hours after drug administration. METH treated rats were divided into high responders (HR) and low responders (LR) based on their stereotypy response. We compared gene expression between HR and LR and between these two groups and saline control.
Experiment types
transcription profiling by array, co-expression, compound treatment, stimulus or stress
Contact
Citation
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MEXP-948.idf.txt
Sample and data relationshipE-MEXP-948.sdrf.txt
Raw data (1)E-MEXP-948.raw.1.zip
Processed data (1)E-MEXP-948.processed.1.zip
Array designA-AFFY-43.adf.txt
R ExpressionSetE-MEXP-948.eSet.r
Links