E-MEXP-772 - Transcription profiling of four mouse cell lines with mutations in the oncogenic tyrosine kinase gene BCR-Abl

Status
Submitted on 5 July 2006, released on 1 August 2007, last updated on 2 May 2014
Organism
Mus musculus
Samples (4)
Array (1)
Protocols (10)
Description
Gene expression profile variation between 4 BCR-Abl transduced cell lines:
1-Mouse DA1-3b cell line as reference,
2-DR1 imatinib resistant clone with E255K BCR-abl mutation
3-DRBMSR 2 dasatinib resistant clone with E255K and T315I BCR-Abl mutation.
4-DRBMSR 7 dasatinib resistant clone with E255K and T315I and V299L BCR-Abl mutation

BCR-ABL is an oncogenic tyrosine kinase involved in the development of chronic myelogenous leukaemia (CML).
Experiment types
transcription profiling by array, loop, strain or line
Contact
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MEXP-772.idf.txt
Sample and data relationshipE-MEXP-772.sdrf.txt
Raw data (1)E-MEXP-772.raw.1.zip
Array designA-AGIL-13.adf.txt
Links