E-MEXP-477 - Transcription profiling of thrombin stimulated human microvascular endothelial cell line-1 (HMEC1) over time and vs untreated cells

Status
Released on 20 January 2006, last updated on 28 May 2012
Organism
Homo sapiens
Samples (29)
Array (1)
Protocols (6)
Description
Thrombin exerts pleiotropic effects on the endothelium. Nevertheless, little is known about its capacity to generate endothelial microparticles, a hallmark of endothelial activation. To gain insight into the mechanisms involved in microparticles release, the human microvascular endothelial cell line-1 (HMEC1) was stimulated with thrombin at 1 IU/ml for different times. The gene expression profiling in stimulated HMEC-1 was compared to that obtain with untreated cells.
Experiment types
 cellular process, physiological process, time series, transcription profiling by array
Contacts
Francine Anfosso <anfosso@pharmacie.univ-mrs.fr>, Dignat-George Francoise, Nguyen catherine, Sampol Jose, Sapet cedric, Simoncini stéphanie
Citations
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MEXP-477.idf.txt
Sample and data relationshipE-MEXP-477.sdrf.txt
Raw data (1)E-MEXP-477.raw.1.zip
Array designA-MEXP-283.adf.txt
Links