E-MEXP-3905 - Transcription profiling by array of human mesenchymal stromal cells from patients with multiple sclerosis before and after autologous hematopoietic stem cell transplantation
Released on 18 September 2013, last updated on 11 March 2015
Transcriptional profile of bone marrow mesenchymal stromal cells isolated from multiple sclerosis patients, before and after autologous hematopoietic stem cell transplantation, and compare to healthy controls.
transcription profiling by array, co-expression, disease state design, ex vivo, transcript identification
Bone marrow mesenchymal stromal cells isolated from multiple sclerosis patients have distinct gene expression profile and decreased suppressive function compared with healthy counterparts. de Oliveira GL, de Lima KW, Colombini AM, Pinheiro DG, Panepucci RA, Palma PV, Brum DG, Covas DT, Simões BP, de Oliveira MC, Donadi EA, Malmegrim KC. Cell Transplant 24(2):151-165 (2015), Europe PMC 24256874