E-MEXP-3890 - Transcription profiling by array of paired synovial macrophages and peripheral blood monocytes from patients with active rheumatoid arthritis
Released on 15 May 2013, last updated on 3 June 2014
Paired synovial and peripheral blood CD14+ cells were obtained from patients with active rheumatoid arthritis and compared to each other
transcription profiling by array, cell type comparison design, co-expression, ex vivo
The Liver X Receptor Pathways is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR driven cytokine release.