E-MEXP-3837 - Transcription profiling following expression of the transcription factor Hoxa2 in first branchial arch cells
Released on 13 December 2013, last updated on 3 June 2014
Branchial arches are transient tissue bands in the head region of all vertebrate embryos. Although initially formed from similar components, each arch will give rise to different head and neck structures.
To understand the molecular control of inter-branchial arch identity, we forced expression of the transcription factor Hoxa2 (the main determinant of second branchial arch fate) in first branchial arch mice cells, and analyzed changes in global expression.
transcription profiling by array, co-expression, in vivo, is expressed
Differential distribution of the ca (2+) regulator pcp4 in the branchial arches is regulated by hoxa2. Anderson M, Amin S, Luise F, Zeef L, Bobola N. PLoS One 8(5):e63160 (2013), Europe PMC 23671666