E-MEXP-3776 - Transcription profiling by array of human fibroblast cell line WI38 overexpressiong the SUMO E3 ligase PIASy to analyse transcriptional changes

Status
Released on 25 July 2013, last updated on 2 October 2013
Organism
Homo sapiens
Samples (6)
Array (1)
Protocols (6)
Description
mRNA profiling of WI38 wild-type or overexpressiong the SUMO E3 ligase PIASy in human primary fibroblasts 24h post-infection. The goal of this study is to analyse transcriptional changes in cells over-expressing the SUMO E3 ligase PIASy and to compare them with ChIPseq data for several histones marks and proteins of the SUMO machinery including PIASy
Experiment types
transcription profiling by array, co-expression, genetic modification design, in vitro, is expressed
Contact
Citation
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation. Neyret-Kahn H, Benhamed M, Ye T, Le Gras S, Cossec JC, Lapaquette P, Bischof O, Ouspenskaia M, Dasso M, Seeler J, Davidson I, Dejean A . Genome Res 23(10):1563 (2013), Europe PMC 23893515
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MEXP-3776.idf.txt
Sample and data relationshipE-MEXP-3776.sdrf.txt
Raw data (1)E-MEXP-3776.raw.1.zip
Array designA-AFFY-141.adf.txt
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