E-MEXP-3767 - Transcription profiling by array of persistent polyclonal B cell lymphocytosis (PPBL) and control IgMpos B cell subsets

Status
Released on 1 July 2013, last updated on 3 May 2014
Organism
Homo sapiens
Samples (19)
Array (1)
Protocols (3)
Description
To study the nature of persistent polyclonal B cell lymphocytosis (PPBL), we purified CD27posIgMposIgDpos from 4 patients, as well as transitional (CD38hiCD24hi), pre-naive (CD38dimCD24dimCD5pos), naive mature (CD38dimCD24dimCD5-CD27-), natural effector (CD27posIgMposIgDpos) and IgM-only (CD27posIgMposIgDneg) B cells from healthy controls and performed genome-wide transcription profiling. We aimed to identify the control counterpart of PPBL cells and to study deregulated processes as compared to this control counterpart
Experiment types
transcription profiling by array, co-expression, development or differentiation, disease state, ex vivo
Contact
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MEXP-3767.idf.txt
Sample and data relationshipE-MEXP-3767.sdrf.txt
Raw data (1)E-MEXP-3767.raw.1.zip
Processed data (2)E-MEXP-3767.processed.1.zip, E-MEXP-3767.processed.2.zip
Array designA-AFFY-44.adf.txt
Links