E-MEXP-3755 - Transcription profiling by array of D. melanogaster whole embryos to investigate localized wound response genes by srine protease-mediated wounding
Released on 12 August 2013, last updated on 15 January 2015
We have used trypsin-mediated wounding to amplify the transcriptional response to clean puncture wounding. We studied the transcriptional response of clean puncture wounding and trypsin puncture wounding in relation to unwounded wild-type late-stage embryos. Trypsin puncture wounding generally increases the puncture wounding fold induction relative to unwounded controls.
transcription profiling by array, co-expression, injury, replicate, time series
Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila. Patterson RA, Juarez MT, Hermann A, Sasik R, Hardiman G, McGinnis W. PLoS One 8(4):e61773 (2013), Europe PMC 23637905