E-MEXP-3736 - Transcription profiling of mouse pancreatic beta-cells with cre-mediated deletion of exon 3 of the B1 integrin gene

Status
Released on 31 July 2013, last updated on 3 May 2014
Organism
Mus musculus
Samples (2)
Array (1)
Protocols (3)
Description
In this study, we investigated the function of beta integrins in developing islet beta-cells by targeting the deletion of exon 3 of the B1 integrin gene using a Cre-lox approach. Our results demonstrate that this class of integrin receptors is critically important for proper beta cell expansion during development
Experiment types
transcription profiling by array, co-expression, genetic modification, in vitro
Contact
Citation
Beta-1 integrin is a crucial regulator of pancreatic beta-cell expansion. Giuseppe R. Diaferia; Antonio J. Jimenez-Caliani; Prerana Ranjitkar; Wendy Yang; Gary Hardiman; Christopher J. Rhodes; Laura Crisa; Vincenzo Cirulli. Development 140(16):3360 (2013), Europe PMC 23863477
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MEXP-3736.idf.txt
Sample and data relationshipE-MEXP-3736.sdrf.txt
Raw data (1)E-MEXP-3736.raw.1.zip
Processed data (1)E-MEXP-3736.processed.1.zip
Array designA-MEXP-933.adf.txt
Links