E-MEXP-3736 - Transcription profiling of mouse pancreatic beta-cells with cre-mediated deletion of exon 3 of the B1 integrin gene

Status
Released on 31 July 2013, last updated on 15 January 2015
Organism
Mus musculus
Samples (2)
Array (1)
Protocols (3)
Description
In this study, we investigated the function of beta integrins in developing islet beta-cells by targeting the deletion of exon 3 of the B1 integrin gene using a Cre-lox approach. Our results demonstrate that this class of integrin receptors is critically important for proper beta cell expansion during development
Experiment types
transcription profiling by array, co-expression, genetic modification, in vitro
Contact
Citation
Beta-1 integrin is a crucial regulator of pancreatic beta-cell expansion. Giuseppe R. Diaferia; Antonio J. Jimenez-Caliani; Prerana Ranjitkar; Wendy Yang; Gary Hardiman; Christopher J. Rhodes; Laura Crisa; Vincenzo Cirulli. Development 140(16):3360 (2013), Europe PMC 23863477
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MEXP-3736.idf.txt
Sample and data relationshipE-MEXP-3736.sdrf.txt
Raw data (1)E-MEXP-3736.raw.1.zip
Processed data (1)E-MEXP-3736.processed.1.zip
Array designA-MEXP-933.adf.txt
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