E-MEXP-3682 - Transcription profiling by array of siRNA silencing of GABPA in MCF10A cells

Status
Released on 15 July 2013, last updated on 2 July 2014
Organism
Homo sapiens
Samples (6)
Array (1)
Protocols (4)
Description
The ETS transcription factor GABPA controls cell migration in breast epithelial cells through targeting a cohort of genes, independently from another family member ELK1, and thereby achieves biological specificity. Here, both direct and indirect target genes for GABPA are identified by siRNA silencing of GABPA. Therefore, although ELK1 and GABPA ultimately control the same biological process, they do so by regulating distinct cohorts of target genes associated with actin cytoskeletal functions and cell migration control.
Experiment types
transcription profiling by array, cellular modification, co-expression, in vivo
Contact
Citation
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MEXP-3682.idf.txt
Sample and data relationshipE-MEXP-3682.sdrf.txt
Raw data (1)E-MEXP-3682.raw.1.zip
Processed data (1)E-MEXP-3682.processed.1.zip
Array designA-AFFY-44.adf.txt
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