E-MEXP-3599 - Transcription profiling by array of M. musculus B16 melanoma cells to investigate gene expression after contacting B-1 lymphocytes (B16B1)
Released on 5 June 2013, last updated on 3 June 2014
Analysis of gene expression patterns in cancer improved the understanding the mechanisms underlying the process of metastatic progression. Recent studies have attributed an important role to B-1 cells, a subset of B lymphocytes, in melanoma progression. It was already demonstrated that in vitro interaction between B16 melanoma cells and B-1 lymphocytes induced increase in metastatic potential of B16 lineage. In this study we used a microarray approach to assess gene expression profile in B16 melanoma cells after contacting B-1 lymphocytes (B16B1).
transcription profiling by array, cellular process, co-expression, in vitro