E-MEXP-3323 - Retinal vessel microarray

Status
Released on 13 September 2013, last updated on 3 June 2014
Organism
Mus musculus, Rattus norvegicus
Samples (24)
Arrays (2)
Protocols (8)
Description
We sought to identify differentially expressed genes in several animal models of a retinal disease exhibiting vascular abnormalities and/or angiogenesis compared to control animals. Retinal microvessels were isolated from three models (RD1, Grhl3ct (Curlytail), VLDLR knock-out) and one rat model (RCS dystrophic rat), as well as from C57BL/J6 mice and non-dystrophic RCS rats as controls. Animals were used at ages appropriate to the age of vascular change of each model. Microvessels were isolated from the retinas and RNA was extracted and used in the microarray.
Experiment types
transcription profiling by array, co-expression, disease state, in vivo, species
Contact
Citation
Apelin is required for non-neovascular remodelling in the retina.
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-MEXP-3323.idf.txt
Sample and data relationshipE-MEXP-3323.sdrf.txt
Raw data (1)E-MEXP-3323.raw.1.zip
Processed data (1)E-MEXP-3323.processed.1.zip
Array designsA-AFFY-43.adf.txt, A-AFFY-45.adf.txt
R ExpressionSetE-MEXP-3323.eSet.r
Links